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Synthesis of 3-Methyl-1-(2-(1-piperidinyl)phenyl)butylamine

LI Guiying1, CHEN Yingchun1, ZHAO Shuang2, MI Haoyu1, WANG Ensi1,2   

  1. 1. College of Pharmacy, Jilin University, Changchun 130021, China; 2. College of Life Science, Jilin University, Changchun 130021, China
  • Received:2006-03-24 Revised:1900-01-01 Online:2007-01-26 Published:2007-01-26
  • Contact: WANG Ensi

Abstract: 3-Methyl-1-(2-(1-piperidinyl)phenyl)butylamine was synthesized from 2- chlorobenzonitrile and 2-fluorobenz aldehyde via two different synthetic routes. The total yields were 42% and 31 %, respectively. The structures of the intermediates and the target compound were confirmed by MS, 1H NMR and 13C-NMR spectra in our experiments.

Key words: 3-methyl-1-(2-(1-piperidinyl)phenyl)butylamine, synthesis, noninsulindependent diabetes mellitus

CLC Number: 

  • R977.15