7-取代-2-氨基-1,2,3,4-四氢-2-萘甲酸的合成

J4 ›› 2010, Vol. 48 ›› Issue (05): 860-864.

Previous Articles Next Articles

Synthesis of 7-Substituted-2-amino-1,2,3,4-tetrahydro-2-naphthalene Carboxylic Acid

CUI Linlin¹, ZHANG Qunli^1,2, MI Haoyu¹, WANG Ensi^1,3

1. College of Life Science, Jilin University, Changchun 130021, China|2. Department of Packaging Engineering, Northeast Forestry University, Harbin 150040, China;3. College of Pharmacy, Jilin University, Changchun 130021, China

Received:2010-02-24 Online:2010-09-26 Published:2010-09-21
Contact: WANG Ensi E-mail:wangss@jlu.edu.cn

Abstract

Abstract:

7-Substituted-2-amino-1,2,3,4-tetrahydro-2-naphthalene carboxylic acid was synthesized through 2tetralone intermediate by hyda
ntoin hydrolysis from the starting materials 7-substituted phenylacetic acid in a total yield of 32%, and hydrolysis conditions of different 7-substituted hydantoin were examined. The structures of the key intermediate and the target mole
cule were confirmed by ¹H NMR and ¹³C NMR.

Key words: 7-substituted-2-amino-1,2,3,4-tetrahydro-2-naphthalene carboxylic acid, synthesis, hydantoin, hydrolysis

CLC Number:

O656.4

CUI Lin-Lin, ZHANG Qun-Li, MI Gao-Yu, WANG En-Sai. Synthesis of 7-Substituted-2-amino-1,2,3,4-tetrahydro-2-naphthalene Carboxylic Acid[J].J4, 2010, 48(05): 860-864.

[1]	LI Erqiang, CHEN Kaijian, ZHOU Yang. Controllable Multi-texture Extended Synthesis and Transfer [J]. Journal of Jilin University Science Edition, 2021, 59(3): 577-586.
[2]	ZHANG Tingyu, CUI Xu, WANG Ying, LI Xuemei, ZHANG Jiayan, ZHUANG Changfu. Synthesis of Ferrocene Porphyrin and Its Substituent Effect [J]. Journal of Jilin University Science Edition, 2021, 59(2): 408-414.
[3]	LIN Hongyan, LI Jiahui, ZENG Ling, WANG Qinglin. Synthesis and Property of AndersonType PolyoxometalateBasedCopper Complex Hybridized by a Tetrazole [J]. Journal of Jilin University Science Edition, 2020, 58(4): 997-1002.
[4]	HUANG Xidai. Fuzzy Region Judgment Algorithm in Network Intrusion [J]. Journal of Jilin University Science Edition, 2020, 58(2): 321-328.
[5]	LIU Rong, WANG Tao, YAO Xin. Selfpropagating Combustion Synthesis and PhotoluminescentProperties of Pure Phase CaAl₄O₇∶Tb³⁺(Sm³⁺)#br# [J]. Journal of Jilin University Science Edition, 2019, 57(1): 166-170.
[6]	LIN Hongyan, ZHAO Jing, LIU Yu, ZENG Ling, WANG Qinglin. Synthesis, Structure and Dye Adsorption Property of OneDimensional[JP]Flexible Bispyridyltetrazolebased Copper Complex [J]. Journal of Jilin University Science Edition, 2018, 56(4): 1012-1016.
[7]	LI Zheng, YU Miao. Synthesis and Fluorescence Properties of Mesotetra(N-alkyl)-carbazolylporphyrins and Their Lanthanide Acetylacetone Complexes [J]. Journal of Jilin University Science Edition, 2016, 54(06): 1445-1450.
[8]	LIU Hong, ZHANG Shugong. Facial Expression Synthesis Based on Curve Representation [J]. Journal of Jilin University Science Edition, 2015, 53(01): 80-88.
[9]	WANG Wei, XIU Zhiming, WANG Deli, XU Tianshu,GUO Youming, WANG Liping. Synthesis and Characterization of Triisopropanolamine Borate [J]. Journal of Jilin University Science Edition, 2014, 52(04): 831-834.
[10]	KONG Weiping, WANG Cong, XU Dandan, ZHAO Li, ZOU Yongcun. High Temperature Hydrothermal Synthesis of PtFunctionalized Mesoporous Al₂O₃ andIts Catalytic Activity for Benzene Combustion [J]. Journal of Jilin University Science Edition, 2014, 52(03): 601-604.
[11]	LIU Hua, WANG Cong, ZOU Xu, LIU Fujian. oft Template Route for Synthesis of Supermicroporous Carbonswith Excellent Adsorption Property for Organic Dye [J]. Journal of Jilin University Science Edition, 2013, 51(06): 1173-1176.
[12]	WANG Yan, REN Dianfu, TIAN Weixing, WANG Hong,CHEN Zhong, HAN Zhaorang. Synthesis and Properties of PolyetherBased Superplasticizer [J]. Journal of Jilin University Science Edition, 2013, 51(05): 949-954.
[13]	PENG Chang-Fu, WANG Ying, ZHANG Jia-Xing, TUN Chun-Hua, TIAN Hang, QIN Yong-Jian, SHI Tong-Shun. Synthesis and Electrochemical Property of an UnsymmetricalPorphyrin and Its Zn Compound [J]. J4, 2012, 50(03): 571-.
[14]	WANG Ban-Ban, SONG Yan-Qiu, Sun-Er-Jun. Synthesis and Organic Photovoltaic Device of Starburst Europium (Ⅲ) β-Diketonate Complex [J]. J4, 2012, 50(02): 351-356.
[15]	YANG Jun, MA Gong-Chao, FU Ying-Huan, SONG Yu, WANG Yong-Wei, XU Chun-Ling, Dong-Xiao-Li. AlkaliActivated Synthesis of Zeolite P from Rice Husk [J]. J4, 2011, 49(04): 767-771.

Synthesis of 7-Substituted-2-amino-1,2,3,4-tetrahydro-2-naphthalene Carboxylic Acid

PDF (PC)

Like

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Metrics

Comments

Recommended 0