Abstract:

Based on the principle of biomimetic synthesis, carbonized hydroxyapatite crystals were prepared by vapor diffusion method with L-serine(L-Ser) and L-aspartic(L-Asp) acted as an organic substrate, and bioinspired enamel repair was performed via L-Ser/Aspdirected assembly of hydroxyapatite
nanoparticles at the same time. The product was characterized by means of field emission scanning electron microscopy (FESEM), X-ray  diffraction (XRD) and Fourier transform infrared spectrometry (FTIR), and the effects of different concentrations of serine on the intermediates of calcium carbonate and final product of calcium hydroxyapatite limestone powder and dental film were studied. The results show that different concentrations of serine significantly affected the morphology of the free crystalline powder in solution, and the conversion of calcium carbonate to hydroxyapatite with morphological hereditary characteristics, as well as played an important role in the continuation of the crystal arrangement on the surface of enamel film.

Key words: enamel, L-serine (L-Ser), L-aspartic (L-Asp), hydroxyapatite (HA), calcium carbonate