Abstract: An unsymmetric porphyrin was synthesized based on the adjustable property of tetraphenylporphyrin. Then, a chiral porphyrin was synthesized by the esterification between the unsymmetric porhyrin and L-BOCphenylalanine. The chiral recognition of the chiral porphyrin with the L and D-alanine methyl ester showed different chiral recognition abilities for small amino acids. The D-alanine methyl ester was more tightly bound to the chiral porphyrin than its optical antipode.

Key words: chiral porphyrin, molecule recognition, amino acid, synthesis