Abstract: Caenorhabditis elegans was used as model to evaluate the antioxidant activities of five kinds of natural food and medicine homologous plants (Rosa roxburghii, Zingiber oj\|jicinale Rosc., Cinnamomum cassia Presl, Dioscoreae rhizoma, grape seeds) by C.elegans lifespan test, oxidative stress test in vitro and free radicals content test in vivo. The results show that 2 mg/mL of R.roxburghii and grape seeds water extractions both can prolong the lifespan of testedC.elegans  remarkably. Five kinds of plant water extractions with different mass concentrations have remarkable repair abilities of oxidative damage and certain free radical scavenging abilities to the tested C.elegans. Among them, the free radical scavenging effects of R.roxburghii and grape seeds water extractions are obvious.

Key words: food and medicine homologous, antioxidant, Caenorhabditis elegans