Abstract:

To discuss the effects of sevoflurane  on perioperative hemodynamics and serum cardiac troponin I(cTnI)  in patients  undergoing abdominal surgery,and offer the reference for selecting anesthetic in clinic.
Methods Forty patients with ASA Ⅱ—Ⅲ,undergoing radical gastrectomy were randomly allocated into sevoflurane group (group S) and propofol group(group P),with each 20 patients.Systemic blood pressure(SBP),diastolic blood pressure(DBP),heart reat(HR) and saturation of oxygen(SPO²) were monitored as routine.The concerntration of cTnI was examined at pre-anesthesia(T¹),post-induction(T²),beginning of operation(T³),end of operation(T⁴),the first day post-operation(T⁵) and the third day post-operation(T⁶) with radioimmunoassay.Results SBP,DBP and HR in group P at  post-induction were significantly lower than those in  group S(P<0.05).The concerntration of cTnI in group P was significantly higher than that in group S at post-induction and the first day post-operation(P<0.05).Conclusion Hemodynamics in sevoflurane group keeps steady during the induction period,and shows  lighter myocardial injury compared with propofol group,the result indicates that perioperative myocardial protection of sevoflurane is  better than that of propofol.

Key words: sevoflurane;anaesthesia,inhalation;propofol;troponin I