Abstract:

Abstract:Objective To evaluate the effect  of porcelain-fused-to-metal(PFM) crowns with different metal alloy base on the gingiva by detecting the IL-6 level in gingival crevicular fluid(GCF). Methods Ni-Cr alloy,gilt Ni-Cr alloy,gold alloy PFM were employed to total of 60 clinical patients. 6 months later,GCF from the patients was collected and quantified,and the IL-6 level was detected by ELISA kit. Results There was no significant difference of the GCF  between gold alloy group and  control group(P>0.05);the GCF in  Ni-Cr alloy group was much higher than those in gold alloy  group and  control group (P<0.05),and there was no significant difference between Ni-Cr alloy group and  gilt Ni-Cr alloy group (P>0.05). The IL-6 levels in GCF in Ni-Cr alloy group was much higher than that in  control group (P<0.05), there were no significant differences between gilt Ni-Cr alloy group,gold allog group and  control group(P>0.05).There was no significant difference  of IL-6 level between gilt Ni-Cr alloy group  and gold alloy group (P>0.05),the IL-6 levels in  gilt Ni-Cr alloy group  and gold alloy group were much lower than that in Ni-Cr alloy  group(P<0.05). Conclusion  Ni alloy has the most serious stimulation,and gold alloy has the least effect on the gingiva.The IL-6 level in GCF could be a theoretical index to monitor clinical effect of PFM.

Key words: porcelain-fused-to-metal;gingival tissue;gingival crevicular fluid;interleukin-6