magnetic resonance (MR) radiomics, machine learning, breast lesions, breast cancer ,"/> 影像组学在乳腺病灶良恶性鉴别中的应用

吉林大学学报(信息科学版) ›› 2023, Vol. 41 ›› Issue (2): 315-320.

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影像组学在乳腺病灶良恶性鉴别中的应用

郑 冲, 李明洋, 兰文婧, 刘香玉, 包 磊, 纪铁凤   

  1. (吉林大学第一医院 放射线科, 长春 130021)
  • 收稿日期:2022-12-25 出版日期:2023-04-13 发布日期:2023-04-16
  • 通讯作者: 纪铁凤(1978— ), 女, 长春人, 吉林大学第一医院副主任医师, 副教授, 硕士生导师, 主要从事乳腺疾病影像组学研究, (Tel)86-13804332730(E-mail)pygcnm@ jlu. edu. cn
  • 作者简介: 郑冲(1994— ), 男, 山东德州人, 吉林大学第一医院硕士研究生, 主要从事乳腺疾病影像组学研究, ( Tel) 86- 15621433350 (E-mail)medicalzc@ 163. com;
  • 基金资助:
    吉林省医疗卫生人才专项基金资助项目(3D5205164428) 

Application of Radiomics in the Diagnosis of Benign and Malignant Breast Lesions

 ZHENG Chong, LI Mingyang, LAN Wenjing, LIU Xiangyu, BAO Lei, JI Tiefeng    

  1. (Department of Radiology, The First Hospital of Jilin University, Changchun 130021, China)
  • Received:2022-12-25 Online:2023-04-13 Published:2023-04-16

摘要:  为探究影像组学方法诊断乳腺病灶良恶性的能力, 比较磁共振(MR: Magnetic Resonance) 影像组学与 传统MR 诊断在良恶性乳腺疾病鉴别中的效能。 回顾分析 2019 年 1 月-2022 年 1 月在吉林大学第一医院放射科 进行乳腺 MR 平扫及增强检查的患者, 收集病理结果证实为良性或恶性的乳腺病灶共 190 例。 MR 影像组学 方法通过建立逻辑回归模型实现诊断; 传统 MR 诊断由一名副高级职称的影像科医生完成。 结果显示测试集 MR 影像组学模型的灵敏度 0. 92, 特异度 0. 83, 曲线下面积(AUC: Area Under Curve)为 0. 92, 以上数值均高于 传统 MR 诊断的对应值, 且差异具有统计学意义(P = 0. 00)。 MR 影像组学的方法可以辅助诊断乳腺病灶的 良恶性, 且诊断效能优于传统 MR 诊断模式。

关键词: MR 影像组学, 机器学习, 乳腺病灶, 乳腺癌

Abstract:  In order to explore the ability of imaging to diagnose benign and malignant breast lesions, and compare the value of MR(Magnetic Resonance) radiomics and traditional MRI(Magnetic Resonance Imaging) in diagnosing breast diseases, a total of 190 cases with benign or malignant breast lesions confirmed by pathological findings are collected from patients who underwent MR Plain and enhanced examination in the Department of Radiology in First Hospital of Jilin University from January 2019 to January 2022. MR radiomics is performed by building logistic regression model. The traditional MR Diagnosis is performed by a radiologist with an associate senior title. The results show that the sensitivity, specificity and AUC (Area Under Curve) of the MR radiomics test set are 0. 92, 0. 83 and 0. 92 respectively. The above values are higher than the corresponding values of traditional MR diagnosis, and the differences are statistically significant ( P = 0. 00 ). The method of MR radiomics can assist in the diagnosis of benign and malignant breast lesions, and the diagnostic ability is better than the traditional MR diagnostic mode.

Key words: magnetic resonance (MR) radiomics')">

magnetic resonance (MR) radiomics, machine learning, breast lesions, breast cancer

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