Abstract: An on-line and sensitive artificial neural network (ANN) analysis combined with flow injection-chemiluminescence (FI-CL) was dev eloped to determine the trace amounts of Au and Pt simultaneously， without the boring process of separating them. Luminol-H_２Ｏ₂ was used as the luminescent reagent. After separation of the most metal ions by cationic exchange resin on-line， EDTA was used as the mask to dispel the effect of residual interference elements. The positions of the catalyzing peak of the luminescence kinetic curve of Au and Pt are different， which is the basis of the simultaneous determination by ANN. The detection limits of Au and Pt were 1.5810^-6　 mmol/L and 2.00×10 ^-3　 mmol/L， respectively， and the relative standard deviation (RSD) were 1.25% and 1.59%. The relative error (RE) of detecting mixed samples is less than 20%.

Key words: artificial neural network, flow injection, chemiluminescence, gold, platinum