J4 ›› 2011, Vol. 49 ›› Issue (04): 782-786.

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UltrasoundPromoted Resolution of(R,S)Glycidyl Butyrate Catalyzed by Lipase

WANG Jiaxin1, SUN Ruoxi2, XUN Erna1, ZHANG Aijun1, WANG Ren1,WEI Xiaofei1, WANG Lei1, WANG Zhi1   

  1. 1. Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, Jilin University,Changchun 130012, China|
    2. College of Life Science, Jilin University, Changchun 130012, China
  • Received:2010-10-15 Online:2011-07-26 Published:2011-08-16
  • Contact: WANG Lei E-mail:wanglei@jlu.edu.cn

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Abstract:

The ultrasound was used to promote the resolution of glycidyl butyrate catalyzed by lipase.  The effects of ultrasound source, ultrasonic processing method, power and temperature were also investigated to obtain the optimum reaction conditions. Under the optimum conditions, the enzyme activity of BSL2 in the resolution of glycidyl butyrate was enhanced by about 4.3fold and the enantioselectivity increased by about 5.0fold.

Key words: ultrasound； lipase； glycidyl butyrate； resolution

CLC Number: 

  • Q814.9
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