Abstract: Aiming at the background of wide application of high-resolution scientific camera and large domestic
demand，a domestic high-resolution scientific CMOS( Complementary Metal Qxide Semiconductor) camera based
on GSENSE400 image sensor of Gpixel company is designed． The camera system includes data acquisition，
control and Camera-Link output design based on FPGA( Field Programmable Gate Array) ． The FPGA mainly
includes SPI ( Serial Peripheral Interface) configuration module，CMOS timing driver module，data acquisition
module，camera link data conversion module and serial communication module． According to the timing logic of
CMOS，the timing design of CMOS driver is implemented in FPGA． According to the amount of HDR( High-
Dynamic Range) image data output by the camera，in order to simplify the design of FPGA data transmission
module，using a DS90CR287 chip，the base mode of Camera-Link is selected for image data transmission，and
the serial port control of the camera is realized． The imaging test is implemented for the designed camara system．
It can output 24 frames continuously in HDR mode with 2 048 × 2 048 pixels，low readout noise，high
sensitivity，high dynamic range image，and basically meet the requirements of scientific level imaging conditions．

Key words: scientific CMOS image sensor, field programmable gate array ( FPGA) , high dynamic range, high
resolution