关键词: 药理学, X线, 睾丸, 酶学, 辐射防护

Abstract: Objective To research the effects of extract of ginger on testis enzymes of X-ray irradiated mice. Methods Mice were treated with three different doses of extract of ginger:high dose (9.3 mL•kg^-1), middle dose (4.7 mL•kg^-1) ，and low dose (2.3 mL•kg^-1). All mice were irradiated once with 2.0 Gy X-ray. At the same time, the negative group (treated with vegetable oil only) and positive one (irradiated as well as extract of ginger groups after treated with vegetable oil) were set up. The changes of activities of enzymes in testes of mice were observed. Results After irradiated, in the group of high dose the activity of G-6-PD was decreased but the activity of LDH was increased (P<0.05); in the group of low dose, the activity of G-6-PD was increased while compared with control group, LDH had no significant difference (P>0.05). In every group, SDH had no significant difference (P>0.05). Conclusion The proper dose of extract of ginger has significant effects on stabilization of testis enzymes of X-ray irradiated mice.

Key words: pharmacology, X-rays, testis, enzymology, radiation protection