Abstract:

Objective To evaluate the value of the new ovarian function marker serum anti-Mullerian hormone(AMH) and to clarify the effect of  hysterectomy  on the ovarian function of the younger women.Methods The serum AMH,follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels  in 35 women suffered uterus benign lesion aged 36-45 years and  35 women suffered hysteromyoma without operation were measured at different time.And the ovarian arterial blood flow resistance index (RI) was measured by Doppler ultrasound.Results Compred with before operation,the serum AMH levels of  the patients in hysterectomy group 2 d and 3 months  after operation were  significantly decreased (P<0.05 or P<0.01).Compared with control group,the serum AMH levels of the patients in hysterectomy group 2 d and 3 months after operation were also decreased(P<0.05).The  ovarian arterial blood flow RI of the patients  in hysterectomy group 1 and 3 months after operation were increased compared with control group(P<0.05).There were no significant differences in the  serum FSH and LH levels  in  each  group between different time points(P>0.05).Conclusion Hysterectomy can affect  the ovarian function,and the  serum AMH level 3 months after operation is decreased and the  ovarian arterial blood flow RI is increased.AMH is  superior to FSH or LH in evaluating the changes of ovarian function.

Key words: anti-Mullerian hormone, hysterectomy, ovarian function