Abstract:

Objective： To investigate the clinical characteristics， diagnosis procedure and treatment method of the patient with recurrent vulvar angiomyofibroblastoma （AMFB），and to improve the understanding of clinical doctors to this disease. Methods The clinical data， imaging examination results， pathological examination results and immunohistochemical examination results of 1 patient with recurrent vulvar AMFB were collected； the above clinical data were analyzed， and the relevant literatures were reviewed. Results A 50-year-old female patient underwent excision of vulvar mass 5 years ago in the local hospital for a vulvar mass，the postoperative pathology suggested AMFB.The patient was now admitted to the hospital due to a 6-month self-reported vaginal mass and a high degree of suspicion of recurrence of AMFB.The gynecological examination suggested a swelling under the labia major on the left side， with complete skin surface， deep protrusion towards the rectum and unclear boundary with the bowel；the size of tumor was about 5.0 cm×4.0 cm×4.0 cm，with regular shape， clear boundary，and poor activity，and there was no obvious tenderness，ulceration and skin lesion. Superficial ultrasound showed a slightly low anechoic light mass with a range of 5.0 cm×4.0 cm×4.0 cm at the left labia major， in which multiple mass hyperechoics were observed. Color Doppler flow imaging （CDFI） showed visible blood flow signals in and around the labia major. Conclusion Although recurrence and malignancy of AMFB are rare， postoperative follow-up of AMFB should be given high priority to reduce the recurrence and increase the cure rate.

Key words: Angiomyofibroblastoma, Vulva, Immunohistochemistry, Recurrence