全固态奎宁选择电极的研制与应用

吉林大学学报(工学版) ›› 2000, Vol. ›› Issue (4): 53-55.

全固态奎宁选择电极的研制与应用

岳京立¹, 于秋泓¹, 汪敏¹, 李东辉¹, 毕丽华²

1. 锦州医学院化学教研室, 辽宁锦州 121001;
2. 吉林工业大学, 理学院, 吉林长春 130025

收稿日期:1999-12-31 出版日期:2000-10-25

Preparation and Application of All-Solid State Quinine Selective Electrode

YUE Jing-li¹, YU Qiu-hong¹, WANG Min¹, LI Dong-hui¹, BI Li-hua ²

1. Dept of Chemistry, Jinzhou Medical College, Jinzhou 121001, China;
2. College of Sciences, Jilin University of Technology, Changchun 130025, China

Received:1999-12-31 Online:2000-10-25

摘要/Abstract

摘要： 首次报道了以奎宁碘化物与碘化铋形成的分子缔合物为电活性物的全固态盐酸奎宁选择电极,电极的线性响应范围为 1.0×10 ^-1～1.0×10^-5 mol/L,级差为 40 mV/pC,检测限为 2.5×10^-6 mol/L。pH值在 3.08～6.10范围内变化时,引起的电势变化不超过±1mV。该电极制作简便、操作灵活、重现性好,结果与药典法相符。

关键词: 奎宁, 离子选择电极, 含量测定

Abstract: In this paper,a new all solid state quinine selective electrode based on quinine and bismuth iodide association complex is reported for the first time.The electrode shows nernst response for quinine with a slope of 40 mV/pC over the concentration range of 1.0×10^-1～1.0×10^-5 mol/L.The detection limit is 2.5×10^-6 mol/L.While pH is at 3.08～6.10,the change of the electrode response does not exceed ±1mV.The electrode possesses fast response and good reproductibility.The procedures of this method are simple and the results obtained agree with those of pharmacopoeia.

Key words: quinine, ion-selective electrode, determination

中图分类号:

O652.2

岳京立, 于秋泓, 汪敏, 李东辉, 毕丽华. 全固态奎宁选择电极的研制与应用[J]. 吉林大学学报(工学版), 2000, (4): 53-55.

YUE Jing-li, YU Qiu-hong, WANG Min, LI Dong-hui, BI Li-hua . Preparation and Application of All-Solid State Quinine Selective Electrode[J]. 吉林大学学报(工学版), 2000, (4): 53-55.

参考文献

[1] 中华人民卫生部药典委员会.中华人民共和国卫生部药典［M］.北京:化学工业出版社, 1985.
[2] 中华人民卫生部药典委员会.中华人民共和国药典(二部)［M］.北京:人民卫生出版社, 1985.
[3] 刘万中,晏哲.奎宁的流动注射离子电极(FIA-ISE) 分析研究［J］.药物分析, 1990, 10(5):261
[4] 李东辉,丁杨栋.聚氯乙烯膜盐酸奎宁选择电极的研制与应用［J］分析化学;1995, 23(11):1271.

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