二苄胺化合物的选择性脱苄基条件

二苄胺化合物的选择性脱苄基条件

付颖寰，李继贞，柏旭，吴劲昌，高澍，吴通好

吉林大学化学学院，长春 130012

收稿日期:2005-03-03 修回日期:1900-01-01 出版日期:2006-01-26 发布日期:2006-01-26
通讯作者: 柏旭

Selective Debenzylation of Dibenzylimine Compounds under Different Conditions

FU Ying-huan, LI Ji-zhen, BAI Xu, WU Jin-chang, GAO Shu, WU Tong-hao

College of Chemistry, Jilin University, Changchun 130012, China

Received:2005-03-03 Revised:1900-01-01 Online:2006-01-26 Published:2006-01-26
Contact: BAI Xu

摘要/Abstract

摘要： 合成了甲氧基取代的二苄基胺化合物，研究其取代基对不同条件下脱苄基方式的影响.在Pd/C加氢条件下，芳环对位上有给电子的甲氧基时，二苄基化合物的断键方式倾向于得到对甲氧基苄胺及萘类芳香烃化合物；而在另外一种氧化条件硝酸铈铵的作用下，二苄基化合物仅从得到萘胺类化合物的方式断键.

关键词: 二苄胺化合物, Pd/C, 硝酸铈铵, 选择性脱苄基

Abstract: Substituted dibenylimine compounds were synthesized and the effects of substituting groups on the cleavage mode of debenzylation under different conditions were also studied. The results indicate that the products of the cleavage under hydrogenation via Pd/C were p-methoxybenzenzylamine and alkanes, while naphthamines were obtained under ceric ammonium nitrate (CAN) oxidation.

Key words: dibenzylimine compound, palladium/C, ceric ammonium nitrate, selective debenzylation

中图分类号:

O623.731

付颖寰，李继贞，柏旭，吴劲昌，高澍，吴通好. 二苄胺化合物的选择性脱苄基条件[J]. J4, 2006, 44(01): 123-125.

FU Ying-huan, LI Ji-zhen, BAI Xu, WU Jin-chang, GAO Shu, WU Tong-hao. Selective Debenzylation of Dibenzylimine Compounds under Different Conditions[J]. J4, 2006, 44(01): 123-125.