流动注射化学发光法测定头孢曲松钠

流动注射化学发光法测定头孢曲松钠

权新军¹, 满文慧², 宋乃忠¹, 郑松志¹, 王洪艳¹, 金为群¹

1. 吉林大学化学学院, 长春 130012； 2. 长春大学生物科学技术学院, 长春 130022

收稿日期:2007-12-26 修回日期:1900-01-01 出版日期:2008-11-26 发布日期:2008-11-26
通讯作者: 金为群

Determination of Ceftriaxone Sodium byFlow Injection Chemiluminescence

QUAN Xinjun¹, MAN Wenhui², SONG Naizhong¹, ZHENG Songzhi¹, WANG Hongyan¹, JIN Weiqun¹

1. College of Chemistry, Jilin University, Changchun 130012, China;2. College of BioScientific and Technical, Changchun University, Changchun 130022, China

Received:2007-12-26 Revised:1900-01-01 Online:2008-11-26 Published:2008-11-26
Contact: JIN Weiqun

摘要/Abstract

摘要： 基于在碱性介质中头孢曲松钠对鲁米诺-K₃Fe(CN)₆化学发光体系的增强作用, 建立了流动注射化学发光测定头孢曲松钠的新方法. 测定范围0.1~400 mg/L, 检出限0.06 mg/L, 对0.2 mg/L头孢曲松钠溶液进行测定, 相对标准偏差为1.6%, 将其用于注射用头孢曲松钠粉针剂的测定, 结果令人满意.

关键词: 头孢曲松钠, 化学发光, 流动注射

Abstract: Ceftriaxone sodium was determined by flow injection chemiluminescence, which is based on the strong enhancement effect of ceftriaxone s odium on LuminolK₃Fe(CN)₆chemiluminescence system in the alkaline medium. Under the optimum conditions, the determination range of method is 0.1~400 mg/L and the detection limit is 0.06 mg/L. The relative standard deviation for the determination of 0.2 mg/L ceftriaxone sodium is 1.6%(n=10). It has been satis factorily applied to the determination of ceftriaxone sodium in the injections.

Key words: ceftriaxone sodium, chemiluminescence, flow injection

中图分类号:

O657.3

权新军, 满文慧, 宋乃忠, 郑松志, 王洪艳, 金为群. 流动注射化学发光法测定头孢曲松钠[J]. J4, 2008, 46(06): 1202-1205.

QUAN Xinjun, MAN Wenhui, SONG Naizhong, ZHENG Songzhi, WANG Hongyan, JIN Weiqun. Determination of Ceftriaxone Sodium byFlow Injection Chemiluminescence[J]. J4, 2008, 46(06): 1202-1205.

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