吉林大学学报(理学版)

• 生命科学 • 上一篇    下一篇

余甘子对秀丽隐杆线虫的抗衰老作用

王丽萍1, 崔雅欣1, 徐佳1, 侯雨菲1, 吐伦阿依·艾合买提1, 王嘉琪1, 王立成2   

  1. 1. 吉林大学 生命科学学院, 长春 130012; 2. 吉林大学 化学学院, 长春 130012
  • 收稿日期:2017-07-14 出版日期:2018-05-26 发布日期:2018-05-18
  • 通讯作者: 王立成 E-mail:wanglc@jlu.edu.cn

Anti-aging Effect of Phyllanthus emblica L.on Caenorhabditis elegans

WANG Liping1, CUI Yaxin1, XU Jia1, HOU Yufei1, Tulunayi·Aihemaiti1, WANG Jiaqi1, WANG Licheng2   

  1. 1. College of Life Sciences, Jilin University, Changchun 130012, China;2. College of Chemistry, Jilin University, Changchun 130012, China
  • Received:2017-07-14 Online:2018-05-26 Published:2018-05-18
  • Contact: WANG Licheng E-mail:wanglc@jlu.edu.cn

摘要: 以模式生物秀丽隐杆线虫(简称线虫)为模型, 考察质量浓度分别为10,20,40 mg/mL[KG*8]的余甘子提取物对线虫的抗氧化作用. 实验结果表明: 10 mg/mL的余甘子提取物能显著提高线虫产卵量, 且对线虫的运动能力无显著影响, 即在实验的质量浓度范围内, 余甘子提取物具有低毒性; 10 mg/mL的余甘子提取物能显著延长线虫的寿命, 并具有抗氧化压力作用; 10 mg/mL的余甘子提取物可显著提高线虫体内过氧化物酶活性, 从而达到抗氧化的保护作用.

关键词: 抗氧化, 秀丽隐杆线虫, 黄酮, 余甘子

Abstract: Based on the model of organism Caenorhabditis elegans, we investigated mass concentration of Phyllanthus emblica L.extracts at 10,20,40 mg/mL on antioxidation of C.elegans. The experimental results show that 10 mg/mL P.emblica L. extract can significantly increase the spawning of C.elegans, and there are no obvious effect on exercise capacity of C.elegans. The P.emblica L.extracts have low toxicity in the mass concentration range of experments. 10 mg/mL P.emblica L.extract can significantly prolong the life of C.elegans, and have a good protective effect on antioxidant pressure. 10 mg/mL P.emblica L.extract can significantly improve the enzyme activity of C.elegans, so as to achieve protective effect of antioxidant.

Key words: Phyllanthus emblica L., Caenorhabditis elegans, flavone, antioxidant

中图分类号: 

  • Q946