新疆锡伯族人群线粒体DNA的遗传学分析

新疆锡伯族人群线粒体DNA的遗传学分析

于长春¹,², 李文荣³，谢力⁴, 张小雷¹, 周慧¹,⁴, 朱泓¹

1. 吉林大学边疆考古研究中心考古DNA实验室, 长春 130012; 2. 吉林师范大学生命科学学院, 吉林省四平 136000; 3. 新疆畜牧科学院，乌鲁木齐 830000; 4. 吉林大学生命科学学院, 长春 130021

收稿日期:2007-01-18 修回日期:1900-01-01 出版日期:2007-09-26 发布日期:2007-09-26
通讯作者: 周慧

Genetic Analysis on Mitochondrial DNA ofXibe Population in Xinjiang

YU Changchun¹,², LI Wen rong³, XIE Li⁴, ZHANG Xiaolei¹, ZHOU Hui¹,⁴, ZHU Hong¹

1. Ancient DNA Laboratory, Research Center for Chinese Frontier Archaeology, Jilin University, Changchun 130012, China;2. College of Life Science, Jilin Normal University, Siping 136000, Jilin Province, China;3. The Xinjiang Academy of Animal Sciences, Wulumuqi 830000, China;4. College of Life Science, Jilin University, Changchun 130021, China

Received:2007-01-18 Revised:1900-01-01 Online:2007-09-26 Published:2007-09-26
Contact: ZHOU Hui

摘要/Abstract

摘要： 分析48个锡伯人线粒体DNA高可变Ⅰ区的遗传多态性, 并与已发表的相关人群线粒体DNA数据进行比较. 结果表明, 在48个序列中共检测出43个突变位点, 界定了35种单倍型, 其线粒体DNA1序列多态性为0.982, 核苷酸多态性为0.018, 而其平均核苷酸差异为5.922. 人群比较分析表明, 锡伯人与古代拓跋鲜卑人有最近的亲缘关系, 同时也表现出与中国北方游牧民族有较近的亲缘关系, 推断锡伯人可能是拓跋鲜卑的后裔.

关键词: 线粒体DNA, 单倍型, 锡伯族, 拓跋鲜卑

Abstract: 48 sequences of hypervariable segment Ⅰ (HVSⅠ) in mitochondrial DNA c ontrol region from Xinjiang Xibe population were analyzed, in which, 35 haplotyp es were found by 43 polymorphic sites. The haplotype diversity and nucleotide di versity are 0.982 and 0.018, respectively, and the mean of nucleotide number dif ferences is 5.922. When the data from relevant populations published were considered, it was found that the Xibe ethnic population presented the closest genetic affinity to ancient Tuoba Xianbei population and, also showed a closer genetic affinity to the nomadic populations from northern China, suggesting that the Xibe people may be the descendants of the ancient Tuoba Xianbei.

Key words: mitochondrial DNA, haplotype, Xibe population, Tuoba Xianbei

中图分类号:

Q987

于长春,, 李文荣，谢力, 张小雷, 周慧,, 朱泓. 新疆锡伯族人群线粒体DNA的遗传学分析[J]. J4, 2007, 45(05): 869-872.

YU Changchun,, LI Wen rong, XIE Li, ZHANG Xiaolei, ZHOU Hui,, ZHU Hong. Genetic Analysis on Mitochondrial DNA ofXibe Population in Xinjiang[J]. J4, 2007, 45(05): 869-872.

[1]	赵天倚, 陈韵, 尹艳春, 邢述, 付学奇. JAK2基因单倍型46/1对中国人群骨髓增殖性肿瘤易感性的影响[J]. 吉林大学学报(理学版), 2016, 54(02): 396-400.
[2]	葛斌文,, 王海晶,, 谢承志,, 崔银秋,, 朱泓, 周慧,. 新疆扎滚鲁克古代人群的线粒体DNA分析[J]. J4, 2008, 46(06): 1206-1210.
[3]	蔡大伟,, 韩璐, 李胜男, 周慧,, 朱泓. 西藏马线粒体DNA Dloop区的遗传多样性[J]. J4, 2007, 45(05): 873-878.
[4]	付玉芹,，，赵晗，许雪莲，崔银秋，张全超，周慧,，朱泓. 内蒙古和林格尔东周时期古代人群的分子遗传学分析[J]. J4, 2006, 44(05): 824-828.
[5]	王海晶, 常娥, 葛斌文, 张全超, 周慧, 朱泓. 饮牛沟墓地古人骨线粒体DNA的研究[J]. J4, 2005, 43(06): 847-852.