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Biodistribution of Quantum Dots in Rats

YANG Rui1, JI Wei2, YAN Yu-xi1,2, FEI Qiang1, MU Ying1,2, JIN Qin-han1   

  1. (1. College of Chemistry, Jilin University, Changchun 130021, China; 2. Key Laboratory for Molecular Enzymology Engineering of Ministry of Education, Jilin University, Changchun 130021, China)
  • Received:2005-08-12 Revised:1900-01-01 Online:2005-11-26 Published:2005-11-26
  • Contact: JIN Qin-han

Abstract: The biological distribution of CdTe nanocrystals in a rat was studied by means of bioanalysis and some laws were obtained. The experiment results indicate that quantum dots are transported by blood circulatory system to liver and spleen, and can be observed in these organs within 24 h which emission wavelength has a red shift. With the time passing, quantum dots distributed in the two organs get less and less till disappearing. By using quantum dots as a tagging to study the transportation, distribution and metabolizing of nanoparticles, the operation is very simple and safe, and the results got directly.

Key words: quantum dot, cadmium telluride, in vivo, biodistribution

CLC Number: 

  • Q136