Abstract:

The adsorption behavior of lysozyme (LYZ) on SBA-15 mesoporous silica with different pore diameters and specific surface areas was inv
estigated.  Adsorption capacities of LYZ were controlled by the specific surface area, and the relationship between the adsorption and the special surface area is q=0.602 53S_BET-130.58. Adsorption kinetic processes were analyzed with three kinds of adsorption reaction models. It wasshown that adsorption kinetics followed the pseudo second order model very well. Adsorption mechanism was analyzed with intraparticle diffusion and simplified external mass transfer diffusion model.  The adsorption rates were dependent upon the pore diameter of mesoporous materials. In certain ranges of pore diameters, the overall adsorption rate and initial adsorption rate of external diffusion increased quickly while intraparticle diffusion rate increased slowly. It was also suggested that SBA15 did not affect the lysozyme structure evidenced by FTIR analysis.

Key words: SBA-15, lysozyme, adsorption kinetics, intraparticle diffusion