药食同源植物醛糖还原酶抑制剂的筛选

Abstract

Abstract:

According to the mechanism of disease of diabetic complication, we selected 50 kinds of medicinal and edible plants, and screened containing effective natural ingredients of aldose reductase inhibitors (ARI). By measuring the IC₅₀ value as a reference, we compared the samples known to inhibit the activity of ARI efficiency in plants. [JP+1]The results show that the ARI activity of lemon, balsam pear, plum and pomegranate are strong. Their IC_50 values are 0.74,0.64,0.25,0.027 mg/mL.

Key words: drug and food source, plant, diabetic complication, aldose reductase inhibitor

CLC Number:

R391

WANG Licheng, ZHANG Peng, XU Jia, LIU Yuting, JIN Ping, WANG Qifei, XIU Zhiming, ZHANG Yue, WANG Liping. Screening of ARI from Medicinal and Edible Plant[J].Journal of Jilin University Science Edition, 2016, 54(03): 652-656.

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Screening of ARI from Medicinal and Edible Plant

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