Abstract: To investigate whether or not aconitine metabolism is affect by sexual distinction, aconitine and its five metabolites were separated from the urine of female and male rabbits and identified after aconitine poisoning by means of liquid chromatographyelectrospray ion trapmass spectrometry (LC-ESI-MS) which is useful in identifying aconitine poisoning in forensic medicine.

Key words: aconitine, metabolite, liquid chromatographyelectrospray ion trapmass spectrometry