基于光电容积脉搏波的无创血糖测量研究

吉林大学学报(信息科学版) ›› 2015, Vol. 33 ›› Issue (1): 52-56.

基于光电容积脉搏波的无创血糖测量研究

刘光达, 蔡靖, 孙茂林, 宋千里, 刘梦婉, 王庆吉

吉林大学仪器科学与电气工程学院, 长春130061

收稿日期:2014-05-09 出版日期:2015-01-24 发布日期:2015-03-20
作者简介:刘光达(1964—), 男, 长春人, 吉林大学教授, 博士生导师, 主要从事光电医疗仪器研究, (Tel)86-13664411920 (E-mail)gdliu@ jlu. edu. cn。
基金资助:
吉林省科技发展计划重点基金资助项目(20120328)

Research on Non-Invasive Blood Glucose Measurement Based on Photoplethysmograph

LIU Guangda, CAI Jing, SUN Maolin, SONG Qianli, LIU Mengwan, WANG Qingji

College of Instrumentation and Electrical Engineering, Jilin University, Changchun 130061, China

Received:2014-05-09 Online:2015-01-24 Published:2015-03-20

摘要/Abstract

摘要：

目前临床使用的血糖测量方法是采用直接抽取患者血液, 根据生物化学反应原理测量血糖, 这种有创测量方法存在疼痛、易感染、不能连续测量等问题。根据光电容积脉搏波检测理论, 研究了一种血糖测量方法,实现临床无创连续血糖测量。该方法采用波长为805 nm 和940 nm 两束近红外光透射患者手指, 其中805 nm为血糖敏感波长, 940 nm 为参考波长。从透射光中提取与血糖有关的信息进行数据处理并进行标定, 计算血糖值。经实验验证, 该方法能实现连续的无创血糖测量。

关键词: 光电容积脉搏波, 近红外光, 无创, 双波长, 血糖测量

Abstract:

The clinical method of blood glucose measurement at present is extracting blood from the patients, which is based on the principle of biochemical reaction. This invasive methord is painful, susceptible and discontinuous. To deal with these problems, we focus on a non-invasive way on the strength of the photoplethysmography detection theory by irradiating the finger with two beams of near infrared lights of 805 nm and 940 nm. The wave of 805 nm is sensitive to glucose, while the 940 nm one acts as the reference. By processing the information of the blood glucose extracted from the transmitted lights, the blood glucose value can be calculated.Experiments have convinced that the continuous non-invasive blood glucose measurement can be achieved.

Key words: photoplethysmography, near-infrared light, non-invasive, dual-wavelength, blood glucose measurement

中图分类号:

TP29

刘光达, 蔡靖, 孙茂林, 宋千里, 刘梦婉, 王庆吉. 基于光电容积脉搏波的无创血糖测量研究[J]. 吉林大学学报(信息科学版), 2015, 33(1): 52-56.

LIU Guangda, CAI Jing, SUN Maolin, SONG Qianli, LIU Mengwan, WANG Qingji. Research on Non-Invasive Blood Glucose Measurement Based on Photoplethysmograph[J]. Journal of Jilin University(Information Science Ed, 2015, 33(1): 52-56.