高脂血症与胆囊结石的关系

doi:吉林省计划委员会资助课题（9762）

高脂血症与胆囊结石的关系

刘雅明¹，吴绥生^1*，尹艳春¹，付昕光²

1. 吉林大学第一医院干部病房，吉林长春130021；2. 长春市朝阳区疾病预防控制中心，吉林长春130021

收稿日期:2005-08-17 修回日期:1900-01-01 出版日期:2006-07-28 发布日期:2006-07-28
通讯作者: 吴绥生

Association between hyperlipemia and gallbladder stones

LIU Ya-ming¹, WU Sui-sheng¹, YIN Yan-chun¹,FU Xin-guang²

1. Department of Cadre Ward,First Hospital，Jilin University,Changchun 130021，China；2. Changchun Center of Disease Prevention and Control in Chaoyang District, Changchun 130021，China

Received:2005-08-17 Revised:1900-01-01 Online:2006-07-28 Published:2006-07-28
Contact: WU Sui-sheng

摘要/Abstract

摘要： 目的:探讨血脂与胆囊结石的关系。方法:对5 982例体检者进行血脂水平的测定，采用超声进行胆囊结石的诊断,比较血脂正常和血脂异常人群胆囊结石的患病情况。结果:高脂血症患者中胆囊结石的检出率(9.86%)高于血脂正常人群（7.00%）（P<0.05）；高脂血症人群胆囊结石的患病风险高于血脂正常的人群(OR＝1.45, 95%CI：1.194～1.771)；高胆固醇血症患者胆囊结石的患病风险较高（OR＝1.653， 95%CI：1.296 ～2.108）；高脂血症患者中性别对胆囊结石的影响不明显（P>0.05，OR＝1.223，95% CI＝0.778～1.921）。结论:高脂血症患者中胆囊结石的患病率高于血脂正常人群；高胆固醇血症患者胆囊结石的患病率高于胆固醇水平正常人群；高脂血症患者中性别对胆囊结石的发生无明显影响。

关键词: 甘油三酯, 总胆固醇, 胆囊结石

Abstract: Objective To study the relationship between plasma lipids and gallbladder stones (GD). Methods The plasma lipids levels were determined and GD was diagnosed by ultrasonic instrument in 5 982 subjects,then the occurrence of GD wa s compared between hyperlipemia and no-hyperlipemia. Results The detectable rate of GD of the hyperlipemia was 9.86% and that of the no-hyperlipemia was 7.00%,the difference was significant (P<0.05)；and the risk of the occurrence of GD of hyperlipemia was higher than no-hyperlipemia (OR＝1.45, 95% CI：1.194-1.771). The sick risk of GD in patients with hypercholesterolemia was much higher than that in persons with abnormal plasma lipids (OR＝1.653， 95%CI：1.296－2.108).Sexes have no influence on the formation of GD in hyperlipemia patients (P>0.05,OR＝1.223 , 95% CI：1.127-2.748). Conclusion The prevalence rate of GD in hy perlipemia patients is higher than that in normal plasma lipids subjects. The sick risk of GD in patients with hypercholesterolemia is much higher than that in persons with normal total cholesterol levels. Sex has no influence on the formation of GD in hyperlipemia patients.

Key words: gloerine, total cholesterol, gallbladder stones

中图分类号:

刘雅明，吴绥生，尹艳春，付昕光. 高脂血症与胆囊结石的关系[J]. J4, 2006, 32(4): 708-710.

LIU Ya-ming, WU Sui-sheng, YIN Yan-chun,FU Xin-guang. Association between hyperlipemia and gallbladder stones[J]. J4, 2006, 32(4): 708-710.

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