J4 ›› 2012, Vol. 50 ›› Issue (4): 812-814.

• 化学 • 上一篇    下一篇

水溶性人参皂苷对秀丽隐杆线虫生物学功能的影响

于笑坤, 何潇潇, 付学奇, 马俊锋   

  1. 1. 吉林农业大学 资源与环境学院, 长春 130118; 2. 赤峰学院 化工学院, 内蒙古 赤峰 024000
  • 出版日期:2012-07-01 发布日期:2012-09-07
  • 通讯作者: 马俊锋 E-mail:mjf@jlu.edu.cn

Effect of Water Soluble Ginsenosides on
Biological Functions of Caenorhabditis elegans

YU Xiaokun, HE Xiaoxiao, FU Xueqi, MA Junfeng   

  1. College of Life Sciences, Jilin University, Changchun 130012, China
  • Online:2012-07-01 Published:2012-09-07
  • Contact: MA Junfeng E-mail:mjf@jlu.edu.cn

摘要:

 以秀丽隐杆线虫作模式生物, 研究水溶性人参皂苷成分对线虫的寿命、 产卵和运动等生命活动的影响. 结果表明: 质量浓度为200 μg/mL的人参皂苷可使线虫寿命延长, 减缓衰老; 质量浓度为500 μg/mL的人参皂苷则对线虫具有一定的毒性作用.

关键词:  秀丽隐杆线虫, 人参皂苷, 衰老

Abstract:

 Soluble ginsenosides with gradient concentrations were added into the culture environment of Caenorhabditis elegans. The effects of ginsenosides on C.elegans were further investigated including lifespan, broodsize, and locomotion. Our results show that 200 μg/mL ginsenosides can increase the lifespan and slow the aging of C.elegans. However, 500 μg/mL ginsenosides induced toxicity to C.elegans.

Key words: Caenorhabditis elegans, ginsenosides, aging

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