基于金纳米颗粒痕量沙丁胺醇的表面增强Raman散射光谱

吉林大学学报(理学版) ›› 2018, Vol. 56 ›› Issue (5): 1247-1250.

基于金纳米颗粒痕量沙丁胺醇的表面增强Raman散射光谱

田艳杰^1, 李代林², 贾翠萍^1, 房雪晴³

1. 中国石油大学（华东）理学院基础物理系, 山东青岛 266555; 2. 中国石油大学（华东）理学院光电科学与工程系, 山东青岛 266555；3. 天津大学材料科学与工程学院, 天津 300350

收稿日期:2018-02-05 出版日期:2018-09-26 发布日期:2018-11-22
通讯作者: 田艳杰 E-mail:tianyj@upc.edu.cn

Surface-Enhanced Raman Scattering Spectra of Trace Amountsof Salbutamol Based on Gold Nanoparticle

TIAN Yanjie¹, LI Dailin², JIA Cuiping¹, FANG Xueqing³

1. Department of Fundamental Physics, College of Science, China University of Petroleum, Qingdao 266555,Shandong Province, China; 2. Department of Optoelectronic Science and Engineering,College of Science, China University of Petroleum, Qingdao 266555, Shandong Province, China;3. School of Materials Science and Engineering, Tianjin University, Tianjin 300350, China

Received:2018-02-05 Online:2018-09-26 Published:2018-11-22

摘要/Abstract

摘要： 用优化的Turkevich方法制备直径为50~60 nm的金纳米颗粒, 并通过表面增强Raman散射技术检测浓度为10^-3~10^-5 mol/L的痕量沙丁胺醇分子. 结果表明: 最低检出限为5×10^-5 mol/L, 在100~750 μmol/L范围内, Raman光谱强度与浓度具有较好的线性关系, 相关系数R²=0.996 57, 但在更宽泛的浓度范围内不满足线性关系; 基于金纳米颗粒表面增强Raman散射光谱方法可实时、快速检测痕量沙丁胺醇分子.

关键词: 表面增强Raman散射, 沙丁胺醇, 金纳米颗粒

Abstract: The gold nanoparticles with diameter of 50—60 nm were prepared by the optimized Turkevich method. The trace amounts of salbutamol molecules with concentrations of 10^-3—10^-5 mol/L were detected by surface-enhanced Raman scattering spectra. The results show that the minimum detection limit is 5×10^-5 mol/L. In the range of 100—750 μmol/L, the Raman intensity and concentration have a good linear relationship, and the correlation coefficient R²=0.996 57, but the Raman intensity and the concentration does not satisfy the linear relationship in a wider concentration range.
The trace amounts of salbutamol molecules can be detected by surface-enhanced Raman scattering method based on gold nanoparticles in real time and rapidly.

Key words: surface-enhanced Raman scattering (SERS), salbutamol, gold nanoparticle

中图分类号:

O433.5

田艳杰, 李代林, 贾翠萍, 房雪晴. 基于金纳米颗粒痕量沙丁胺醇的表面增强Raman散射光谱[J]. 吉林大学学报(理学版), 2018, 56(5): 1247-1250.

TIAN Yanjie, LI Dailin, JIA Cuiping, FANG Xueqing. Surface-Enhanced Raman Scattering Spectra of Trace Amountsof Salbutamol Based on Gold Nanoparticle[J]. Journal of Jilin University Science Edition, 2018, 56(5): 1247-1250.

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