Journal of Jilin University Science Edition

Previous Articles     Next Articles

Effects of Ultrasonic Pretreatment on Enzymatic Resolution of Ibuprofen

AN Baiyi1, ZHENG Lu2, WU Zhuofu2,3, WANG Lei2, WANG Zhi2, CHEN Guang3   

  1. 1. College of Horticulture, Jilin Agricultural University, Changchun 130118, China;2. Key Laboratory of Molecular Enzymology and Engineering of Ministry
     of Education, Jilin University, Changchun 130012, China;3. College of Life Science, Jilin Agricultural University, Changchun 130118, China
  • Received:2016-03-24 Online:2016-09-26 Published:2016-09-19
  • Contact: WANG Zhi E-mail:wangzhi@jlu.edu.cn

PDF (PC)

137

Like

Abstract:

We studied the effects of ultrasonic pretreatment power, pretreatment temperature, ultrasonic pretreatment time, and the reaction conditions of water activity and pH on the enzymatic resolution of ibuprofen, and obtained the optimum reaction conditions for the enzymatic resolution of ibuprofen. Experimental results show that the cataytic performance of enzyme can be greatly improved by ultrasonic pretreatment.

Key words: ultrasonic pretreatment； APE1547 enzyme； ibuprofen, stereoselectivity, enzyme activity

CLC Number: 

  • Q814.9
Copyright © Journal of Jilin University Science Edition, All Rights Reserved.
Tel: +86-431-88499428　E-mail: sejuj@jlu.edu.cn
Powered by Beijing Magtech Co. Ltd