[1] Guariguata L,Whiting DR,Hambleton I,et al. Global estimates of diabetes prevalence for 2013 and projections for 2035[J]. Diabetes Res Clin Pract,2014,103(2):137-149.
[2] Bartel DP.MicroRNAs:genomics,biogenesis,mechanism,and function[J].Cell,2004,116(2):281-297.
[3] Kaviani M,Azarpira N,Karimi MH,et al.The role of microRNAs in islet β-cell development[J].Cell Biol Int,2016,40(12):1248-1255.
[4] Gauthier BR,Wollheim CB.MicroRNAs:ribo-regulators of glucose homeostasis[J].Nat Med,2006,12(1):36-38.
[5] Lynn FC,Skewes-Cox P,Kosaka Y,et al.MicroRNA expression is required for pancreatic islet cell genesis in the mouse[J].Diabetes,2007,56(12):2938-2945.
[6] Sebastiani G,Vendrame F,Dotta F.MicroRNAs as new tools for exploring type 1 diabetes:relevance for immunomodulation and transplantation therapy[J].Transplant Proc,2011,43(1):330-332.
[7] Ventriglia G,Nigi L,Sebastiani G,et al.MicroRNAs:Novel players in the dialogue between pancreatic islets and immune system in autoimmune diabetes[J].Biomed Res Int,2015,2015:749734.
[8] Zulewski H.Stem cells with potential to generate insulin producing cells in man[J].Swiss Med Wkly,2006,136(41/42):647-654.
[9] Lin PY,Hung SH,Yang YC,et al.A synthetic peptide-acrylate surface for production of insulin-producing cells from human embryonic stem cells[J].Stem Cells Dev,2014,23(4):372-379.
[10] Sulzbacher S,Schroeder IS,Truong TT,et al.Activin A-induced differentiation of embryonic stem cells into endoderm and pancreatic progenitors-the influence of differentiation factors and culture conditions[J].Stem Cell Rev,2009,5(2):159-173.
[11] Wei R,Yang J,Liu GQ,et al.Dynamic expression of microRNAs during the differentiation of human embryonic stem cells into insulin-producing cells[J].Gene,2013,518(2):246-255.
[12] Lahmy R,Soleimani M,Sanati MH,et al.Pancreatic islet differentiation of human embryonic stem cells by microRNA overexpression[J].J Tissue Eng Regen Med,2016,10(6):527-534.
[13] Guay C,Regazzi R.New emerging tasks for microRNAs in the control of β-cell activities[J].Biochim Biophys Acta,2016,1861(12 Pt B):2121-2129.
[14] Wang L,Huang Y,Guo Q,et al.Differentiation of iPSCs into insulin-producing cells via adenoviral transfection of PDX-1,NeuroD1 and MafA[J].Diabetes Res Clin Pract,2014,104(3):383-392.
[15] Alipio Z,Liao W,Roemer EJ,et al.Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic-beta-like cells[J].Proc Natl Acad Sci U S A,2010,107(30):13426-13431.
[16] Sebastiani G,Valentini M,Grieco GE,et al.MicroRNA expression profiles of human iPSCs differentiation into insulin-producing cells[J].Acta Diabetol,2017,54(3):265-281.
[17] Shaer A,Azarpira N,Karimi MH,et al.Differentiation of human-induced pluripotent stem cells into insulin-producing clusters by microRNA-7[J].Exp Clin Transplant,2016,14(5):555-563.
[18] Shaer A,Azarpira N,Karimi MH.Differentiation of human induced pluripotent stem cells into insulin-like cell clusters with miR-186 and miR-375 by using chemical transfection[J].Appl Biochem Biotechnol,2014,174(1):242-258.
[19] Liu J,Liu Y,Wang H,et al.Direct differentiation of hepatic stem-like WB cells into insulin-producing cells using small molecules[J].Sci Rep,2013,3:1185.
[20] Meivar-Levy I,Sapir T,Berneman D,et al.Human liver cells expressing albumin and mesenchymal characteristics give rise to insulin-producing cells[J].J Transplant,2011,2011:252387.
[21] Li R,Oka K,Yechoor V.Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer[J].J Vis Exp,2012(68).doi:10.3791/4321.
[22] Wang AY,Ehrhardt A,Xu H,et al.Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver[J].Mol Ther,2007,15(2):255-263.
[23] Lu J,Dong H,Lin L,et al.miRNA-302 facilitates reprogramming of human adult hepatocytes into pancreatic islets-like cells in combination with a chemical defined media[J].Biochem Bioph Res CO,2014,453(3):405-410.
[24] Heo JS,Choi Y,Kim HS,et al.Comparison of molecular profiles of human mesenchymal stem cells derived from bone marrow,umbilical cord blood,placenta and adipose tissue[J].Int J Mol Med,2016,37(1):115-125.
[25] Milanesi A,Lee JW,Xu Q,et al.Differentiation of nestin-positive cells derived from bone marrow into pancreatic endocrine and ductal cells in vitro[J].J Endocrinol,2011,209(2):193-201.
[26] Jafarian A,Taghikhani M,Abroun S,et al.Generation of high-yield insulin producing cells from human bone marrow mesenchymal stem cells[J].Mol Biol Rep,2014,41(7):4783-4794.
[27] Bai C,Gao Y,Li X,et al.MicroRNAs can effectively induce formation of insulin-producing cells from mesenchymal stem cells[J].J Tissue Eng Regen Med,2017,11(12):3457-3468.
[28] Poy MN,Eliasson L,Krutzfeldt J,et al.A pancreatic islet-specific microRNA regulates insulin secretion[J].Nature,2004,432(7014):226-230.
[29] Fu X,Jin L,Wang X,et al.MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation[J].Proc Natl Acad Sci U S A,2013,110(44):17892-17897.
[30] Piran M,Enderami SE,Piran M,et al.Insulin producing cells generation by overexpression of miR-375 in adipose-derived mesenchymal stem cells from diabetic patients[J].Biologicals,2017,46:23-28.
[31] Mu C,Wang T,Wang X,et al.Identification of microRNAs regulating Hlxb9 gene expression during the induction of insulin-producing cells[J].Cell Biol Int,2016,40(5):515-523.
[32] Jafarian A,Taghikani M,Abroun S,et al.The generation of insulin producing cells from human mesenchymal stem cells by miR-375 and anti-MiR-9[J].PLoS One,2015,10(6):e0128650.
[33] Teng C,Guo Y,Zhang H,et al.Identification and characterization of label-retaining cells in mouse pancreas[J].Differentiation,2007,75(8):702-712.
[34] Bai C,Li X,Gao Y,et al.Role of microRNA-21 in the formation of insulin-producing cells from pancreatic progenitor cells[J].Biochim Biophys Acta,2016,1859(2):280-293. |
