草本水杨梅中芳香类化合物的分离与鉴定

doi:国家留学基金委资助课题(19995003)

草本水杨梅中芳香类化合物的分离与鉴定

李刚，杨晓虹^*，王艳，牟凤辉，董雷，陈滴，李怀林

吉林大学药学院药物化学教研室，吉林长春 130021

收稿日期:2005-07-04 修回日期:1900-01-01 出版日期:2006-03-28 发布日期:2006-03-28
通讯作者: 杨晓虹^*

Isolation and structure identification of phenoliccompounds from Geum aleppicum Jacq.

LI Gang,YANG Xiao-hong^*, WANG Yan,MU Feng-hui,DONG Lei, CHEN Di, LI Huai-lin

Department of Medicinal Chemistry, School of Pharmacy, Jilin University,Changchun 130021,China

Received:2005-07-04 Revised:1900-01-01 Online:2006-03-28 Published:2006-03-28
Contact: YANG Xiao-hong^*

摘要/Abstract

摘要： 目的：分离和鉴定草本水杨梅中芳香类化合物。方法：采用薄层色谱分析、硅胶柱色谱法纯化，经理化常数、光谱学方法分离鉴定6个化合物的结构。结果：从草本水杨梅全草中共分离得到6个芳香类化合物，分别确定其结构为苯甲酸(Ⅰ)、没食子酸(Ⅱ)、水杨酸(Ⅲ)、香草醛(Ⅳ)、3，4，5-三羟基苯甲醛(Ⅴ)、3，4，5-三羟基苯甲酸乙酯(Ⅵ)。结论：化合物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ均为首次从草本水杨梅中分得的芳香类化合物。

关键词: 分离鉴定, 芳香化合物

Abstract: Objective To isolate and identify the structures of the phenolic compounds from Geum aleppicum Jacq..Methods The structures of six compouds were determined by the physical and chemical data and spectroscopic analysis after the purification by thin-layer chromotography and silical gel column chromatography. Results Six phenolic compounds were isolated from Geum aleppicum Jacq.,and their structures were established to be benzoic acid (Ⅰ),gallate acid (Ⅱ),salicylic acid (Ⅲ),vanilin (Ⅳ),3,4,5-trihydoxybenzoic dehyde(Ⅴ) and 3,4,5-trihydoxybenzoic acid,ethyl ester (Ⅵ). Conclusion The compounds Ⅰ,Ⅱ,Ⅲ,Ⅳ,Ⅴ,Ⅵ are isolated from this plant for the first time.

Key words: isolation and idetification, aromatic hydrocarbons

中图分类号:

O656

李刚，杨晓虹，王艳，牟凤辉，董雷，陈滴，李怀林. 草本水杨梅中芳香类化合物的分离与鉴定[J]. J4, 2006, 32(2): 196-198.

LI Gang,YANG Xiao-hong, WANG Yan,MU Feng-hui,DONG Lei, CHEN Di, LI Huai-lin. Isolation and structure identification of phenoliccompounds from Geum aleppicum Jacq.[J]. J4, 2006, 32(2): 196-198.