关键词: 骨引导作用, 引导性骨再生术

Abstract: Abstract:Objective To obtain the calcinated bone ceramics used for bone defects repair with a good biological compatibility and bone guidance function,and study its physicochemical characteristics in order to find ideal stent for bone defects repair. Methods The ox bone was calcinated to remove the organic principle,the antigenicity and the pathogenic microorganisms. The inorganic principle which was same to the human bone was retained to maintain the crude 3D communication structure. After pretreatment the ox bone was calcinated to 850℃ and became the granular. The physicochemical characteristics and chemical composition were determined by X-ray diffraction,electron microprobe,inductively coupled plasma atomic spectrometry,electron microscopy and photoelectron spectrometry. Results Hydroxyapatite(HAP) was the main composition of the calcinated bone ceramics determined by X-ray diffraction. No nitrogen was detected by inductively coupled plasma atomic spectrometry. This result showed that there was not protein and organic principles in the calcinated bone ceramics. The crude bone trabecular,trabecular bone cavity and space system were observed clearly by scanning electron microscope. The pore size was 200~850 μm. The average porosity was 84.9%±0.6%. Conclusion There are 3D communication pore structure in calcinated bone ceramics.The main composition of calcinated bone ceramics is hydroxyapatite.It has good tissue compatibility.So calcinate bone ceramics is an ideal material for bone repair.

Key words: bone guidance function, guided bone regeneration