关键词: 诊断, 脂蛋白（A）, 诊断应用, C反应蛋白, 诊断应用, 纤维蛋白原, 诊断应用, 危险因素

Abstract: Objective To investigate the relationship between the serum C-reative protein (CRP),lipoprotein(a)［LP(a)］ fibrinogen (FG)and elderly acute cerebral infarction. Methods 106 elderly patients and 70 healthy elderly persons as control were enrolled in this study.The serum CRP,LP(a) and FG levels were determined with immunoturbidimetry and compared among various severe degree and infarct size groups. Results ①Compared with control group,the serum CRP,LP(a) and FG levels in elderly acute cerebral infarction group increased significantly;they were (14.06±2.17) mg•L^-1,(322.34±6.31) mg•L^-1and (8.24±2.62) g•L^-1,resp ectively(P<0.05).② The serum CRP,LP(a)and FG levels were different among various infarct size groups,large infarct size group>small infarct size group>lacunar infarction group (P<0.05 or P<0.01).③The serum CRP,LP(a),FG leve ls were different among various severe degree groups,serious group>midrange group>mild group (P<0.05 or P<0.01).Conclusion The relationship between the serum CRP,LP(a) and FG levels and degree of acute cerebral infarction in elderly patients is intimate.The higher the serum CRP,LP(a) and FG levels were,the larger the infarct size and the more severe the pathogenetic condition.So the serum CRP,LP(a) and FG levels are risk factors for acute cerebral infarction and used to evaluate the severity and infarct size of acute cerebral infarction in elderly patients.

Key words: diagnosis, lipoprotein(A), diagnosis use, C-reactive protein, diagnosis use, fibrinogen, diagnosis use, risk factor