J4

• 基础医学 • 上一篇    下一篇

豚鼠不同部位引导的40 Hz相关电位特点的对比

刘淑芳, 付仲鹰, 史东光   

  1. 吉林大学第一医院耳鼻咽喉-头颈外科,吉林 长春 130021)
  • 收稿日期:2007-11-30 修回日期:1900-01-01 出版日期:2008-07-28 发布日期:2008-07-28
  • 通讯作者: 刘淑芳

Comparison between 40Hz potential from vertex and 40Hz potential from round window in guinea pigs

LIU Shu-fang,FU Zhong-ying,SHI Dong-guang   

  1. (Department of Otorhinolaryngology and Head-Neck Surgery,First Hospital,Jilin University,Changchun 130021,China)
  • Received:2007-11-30 Revised:1900-01-01 Online:2008-07-28 Published:2008-07-28
  • Contact: LIU Shu-fang

摘要: 目的: 对比观察从豚鼠不同部位引导的40Hz相关电位的特点,为临床低频听力检测提供适宜指标。方法: 采用适宜的参数即带通滤波为8~30Hz,刺激间隔为25 ms,扫描时间为100 ms从豚鼠的颅顶和圆窗同步记录听觉中潜伏期40Hz相关电位和听觉早潜伏期40Hz相关电位(40Hz AERP-MLR和40Hz AERP-ELR)。结果:两种电位的共同特点是频率响应好,波形稳定,易辨认。圆窗的40Hz AERP-ELR较颅顶的振幅高,反应阈值低,特别是低频的反应阈值低,在0.5 kHz短纯音时听阈可达到(14.15±6.06)dBnHL。而颅顶40Hz AERP-MLR的反应阈值则是(43.50±9.65) dBnHL,明显高于圆窗反应阈值(P<0.01)。结论: 经圆窗引导的40Hz AERP-ELR在低频听力检测中优于颅顶,为临床低频听力检测提供一项较好的客观指标。

关键词: 听觉, 颅顶, 圆窗

Abstract: To compare the characteristics between two kinds of 40Hz auditory evoked potentials and provide suitable index for clinical auditory test of low-fre quency. Methods The potentials including 40Hz auditory event related potential of middle latency response(40Hz AERP-MLR) and 40Hz auditory event related potential of early latency response(40Hz AERP-ELR) from window and vertex were recorded in guinea pigs. Results The common characteristics of the potentials were good frequency response,easy identification and lower responsive thresholds.Amplitude of 40Hz AERP-ELR was higher and threshold was lower than 40Hz AERP-MLR,especially 0.5kHz tone burst,which was (14.15±6.06)dBnHL.In vertex,the threshold of 40Hz AERP-MLR was (43.50±9.65)dBnHL,which was higher than that in round window(P<0.01). Conclusion 40Hz AERP-ELR recorded from round window is better than from vertex in low-frequency test. The experiment results indicate that the responses provide ideal index for clinical auditory test of low-frequency.

Key words: auditory, vertex, round window

中图分类号: 

  • R-332