关键词: 碳, 硅棕胶, 生存期

Abstract: Objective To investigate the feasibility of using a new type carina type tracheal prosthesis made of complex material to replace trachea and carina defects. Methods According to biomechanics index, a new carina type tracheal prosthesis was designed and constituted with carbon fiber and silicon. 19 dogs were divided into two groups randomly: group A(n=11), the carina type tracheal prosthesis anastomosed directly to dog′s trachea and bronchus;group B(n=8), based on group A, meanwhile the diaphragm was incised and the pedicel caul was transplanted from abdominal cavity to thorax to enwrap the carina type tracheal prosthesis and anastomotic site.Results The average survival period post operation in group A and group B were (3.462±1.849)d and (6.475±1.062)d, respectively. There was significant difference of the survival period between two groups(P<0.05). The anastomose dehiscence: group A was（37.5±36.0）% ; group B was（16.0±25.0）%, there was significant difference (P<0.05). Conclusion Using the pedicel caul to enwrap the carina type tracheal prosthesis and anastomotic site can reduce the degree of anastomose dehiscence and prolong the survival period of the experimental dogs, but how to prevent the prosthesis shift and anastomose dehiscence will be still a most question to be settled.

Key words: carbon, silastic, survival period