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葡萄糖酸钙和乳酸钙在大鼠体内的吸收和利用

甘振威,张娅婕,陈秋丽,刘华锋,马萱钺*   

  1. 吉林大学公共卫生学院营养与食品卫生学教研室,吉林 长春130021
  • 收稿日期:2003-07-08 修回日期:1900-01-01 出版日期:2004-07-28 发布日期:2004-07-28
  • 通讯作者: 马萱钺

Absorption and utilization of calcium gluconateand calcium lactate in rats in vivoGAN Zhen-wei,

ZHANG Ya-jie, CHEN Qiu-li, LIU Hua-feng, MA Xuan-yue*   

  1. Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun 130021,China
  • Received:2003-07-08 Revised:1900-01-01 Online:2004-07-28 Published:2004-07-28
  • Contact: MA Xuan-yue

摘要: 目的:探讨葡萄糖酸钙和乳酸钙在大鼠体内的吸收和利用。方法:断乳雄性Wistar大鼠50只,随机分成5组,分别用碳酸钙、奶粉钙、葡萄糖酸钙和乳酸钙配制的饲料及基础低钙饲料喂养动物28 d,并分别在第20天和第25天进行3 d食物效价实验及4 d钙代谢实验。 结果:葡萄糖酸钙组大鼠体重增长率为92.1%,钙吸收率及储留率分别为68.2%和85.1%,股骨指数为4.96, 股骨钙存留率为4.6%,各项指标均低于奶粉钙组,高于碳酸钙组(P<0.05或P<0.01)。乳酸钙组大鼠体重增长率为75.1%,钙吸收率及储留率分别为65.5 %和82.0%,股骨指数为4.88,股骨钙储留率为4.1%,优于碳酸钙组(P<0.05或P<0.01),乳酸钙组除体重增长率低于葡萄糖酸钙组外,其他指标与葡萄糖酸钙组比较差异无显著性。 结论:葡萄糖酸钙和乳酸钙均可以作为机体的良好钙源,应用于食品添加剂和药物。

关键词: 代谢, 乳酸钙, 大鼠, Wistar

Abstract: Objective To study the absorpion and utilization of calcium gluconate and calcium lactate in rats in vivo. Methods Weaning male Wistar rats were randomly divided into 5 groups and fed on CaCO3, skimmed milk powder, calcium gluconate, calcium lactate, and basic low calcium meal in semi-purified diets, respectively, for 4 weeks. Meanwhile,the experiments of 3 days′ feed efficiency and 4 days′ calcium metabolism were carried out on the 20th and 25th day, respectively. Results In calcium-gluconate group, the incremental rate of body weight,the absorption and retention rate of calcium,the femur index, and retention rate of calcium in femur were 92.1%,68.2%,85.1%,4.96, and 4.6%, respectively, all indexes were lower than those in milk-powder group and higher than those in CaCO3 group (P<0.05 or P<0.01). The items mentioned above in calcium-lactate group were 75.1%,65.5%,82.0%,4.88 and 4.1%, respectively,also higher than those in CaCO3 group (P<0.05 or P<0.01),no differences were found between calcium-gluconate group and calcium-lactate group except that the incremental rate of body weight in calcium-lactate group was lower than that in calcium-gluconate group.Conclusion Both calcium gluconate and calcium lactate can be served as the good sources for dietary calcium supplement.

Key words: metabolism, calcium lactate, rats, Wistar

中图分类号: 

  • R-332