二维应变超声心动图定量评价糖尿病患者左室纵向局部心肌功能

J4 ›› 2010, Vol. 36 ›› Issue (3): 582-585.

二维应变超声心动图定量评价糖尿病患者左室纵向局部心肌功能

丛志斌^1|2, 任卫东¹, 李宏宇³, 杨玉洁², 姜镔¹

(1.中国医科大学附属盛京医院超声科,辽宁沈阳 110004； 2.长春中医药大学附属医院电诊科,吉林长春 130021；3.吉林省人民医院检验科|吉林长春 130021)

收稿日期:2009-12-30 出版日期:2010-05-28 发布日期:2009-05-28
通讯作者: 任卫东 E-mail:renweidong01@yahoo.com.cn
作者简介:丛志斌(1972-),女|山东省蓬莱市人|副主任医师|医学博士| 主要从事心血管超声诊断研究。
基金资助:
吉林省科技厅科研基金资助课题（200805113）

Quantitative assessment of two dimensional strain echocardiography in long-axis regional systolic function of left ventricle in |patients with diabetes mellitus

CONG Zhi-Bin^1,2, LIN Wei-Dong¹, LI Hong-Yu³, YANG Yu-Ji², JIANG Bin¹

(1. Department of Ultrasound,Sheng Jing Hospital, China Medical University,Shenyang 110001,China;2. Department of Electrodiagnosis,Affiliated Hospital,Changchun University of |Chinese Medicine,Changchun 130021,China;3. Department of Laboratory,People’s Hospital,Jilin Province,Changchun 130021,China)

Received:2009-12-30 Online:2010-05-28 Published:2009-05-28

摘要/Abstract

摘要：

目的：应用二维应变超声心动图(2D-SE) 研究左室射血分数正常的2型糖尿病患者左室纵向局部心肌功能改变，探讨2D-SE的临床应用价值。方法：应用GE Vivid 7-Dimension 超声心动图仪分别采集30例糖尿病患者与30例正常对照者心尖左室长轴、心尖四腔和心尖左室二腔观的二维灰阶动态图像。应用自动功能成像软件（AFI）自动测量长轴方向左室18 节段收缩峰值应变。结果：糖尿病组和对照组左室舒张末容积(LVEDV)、左室收缩末容积(LVESV)每搏输出量(SV)及左室射血分数均在正常范围，两组比较差异无显著性（P＞0.05）。与对照组比较，糖尿病组左室18节段收缩期纵向峰值应变显著降低,各个节段组间比较差异有显著性(均P <0.01) 。结论：糖尿病患者左室纵向局部心肌收缩功能受损常早于整体收缩功能出现障碍。2D-SE可以用来定量评价左室射血分数正常的糖尿病患者左室局部心肌功能改变。

关键词: 二维应变超声心动图；糖尿病；左心室功能

Abstract:

Abstract:Objective
To assess the long-axis regional systolic function of the left ventricle (LV) in patients with type 2 diabetes mellitus ( T2DM) using two-dimensional strain echocardiography（2D-SE）and explore clinical application value of 2D-SE.Methods 30 T2DM patients with normal LV ejection fraction (LVEF≥55%), 30 normal controls were selected.The peak strain of segments in apical long-axis, four-chamber,and two-chamber views were evaluated,and average peak strain in the long axis at basal,middle and apical levels were assessed by automated functional imaging(AFI).Results LVEDV,LVESV,SV and LVEF in T2DM patients and normal controls were all within normal limits.Furthermore,there was no significant difference between the two groups (P＞0.05).Compared with normal controls, the peak strain at each plane in T2DM patients was significantly reduced (P<0.01).Conclusion The long-axis regional systolic function of LV in the patients with T2DM is impaired ahead of global systolic function disturbance. 2D-SE may be used to identify early abnormalities of systolic function in T2DM patients with normal LVEF.

Key words: two-dimensional strain echocardiography;diabetes mellitus;left ventricular function

中图分类号:

R445.1

丛志斌, 任卫东, 李宏宇, 杨玉洁, 姜镔. 二维应变超声心动图定量评价糖尿病患者左室纵向局部心肌功能[J]. J4, 2010, 36(3): 582-585.

CONG Zhi-Bin, LIN Wei-Dong, LI Hong-Yu, YANG Yu-Ji, JIANG Bin. Quantitative assessment of two dimensional strain echocardiography in long-axis regional systolic function of left ventricle in |patients with diabetes mellitus[J]. J4, 2010, 36(3): 582-585.