冠状动脉疾病报告与数据系统在冠心病患者危险因素分析中的应用

doi:10.13481/j.1671-587x.20170329

吉林大学学报(医学版) ›› 2017, Vol. 43 ›› Issue (03): 617-622.doi: 10.13481/j.1671-587x.20170329

冠状动脉疾病报告与数据系统在冠心病患者危险因素分析中的应用

周宏¹, 刘进才¹, 罗光华¹, 谢佩含¹, 杨娟¹, 董宇岚¹, 卿伟鹏¹, 张晶晶²

1. 南华大学附属第一医院放射科, 湖南衡阳 421001;
2. 南华大学附属第一医院心血管内科, 湖南衡阳 421001

收稿日期:2016-09-06 出版日期:2017-05-28 发布日期:2017-06-01
通讯作者: 刘进才,教授,硕士研究生导师(Tel:0734-8578912,E-mail:liujincai6353@163.com) E-mail:liujincai6353@163.com
作者简介:周宏(1983-),男,湖南省常德市人,医学博士,主治医师,主要从事CT、磁共振新技术的临床应用和心血管药物药理学以及新药开发方面的研究。
基金资助:
湖南省科技厅科技项目重点研发计划资助课题（2015SK2046）；湖南省教育厅科学研究重点项目资助课题（14A126）；湖南省衡阳市科技局科技发展计划项目资助课题（2015KJ40）

Application of Coronary Artery Disease-Reporting and Data System in risk factor analysis of patients with coronary artery disease

ZHOU Hong¹, LIU Jincai¹, LUO Guanghua¹, XIE Peihan¹, YANG Juan¹, DONG Yulan¹, QING Weipeng¹, ZHANG Jingjing²

1. Department of Radiology, First Affiliated Hospital, University of South China, Hengyang 421001, China;
2. Department of CardiovascularMedicine, First Affiliated Hospital, University of South China, Hengyang 421001, China

Received:2016-09-06 Online:2017-05-28 Published:2017-06-01

摘要/Abstract

摘要： 目的：探讨冠状动脉疾病报告与数据系统（CAD-RADS）在冠状动脉粥样硬化性心脏病（冠心病）诊断中的应用及其危险因素，阐明危险因素对CAD-RADS诊断冠心病的影响强度。方法：收集266例临床怀疑冠心病患者的冠状动脉CT血管造影（CTA）影像资料和临床相关资料，采用CAD-RADS分级法将患者分为冠心病组（n=174）和非冠心病组（n=69）。分析2组患者年龄、性别、高血压、高血脂、糖尿病、吸烟、尿酸（UA）水平和血浆纤维蛋白原（FIB）水平；采用单因素和多因素Logistic回归分析方法分析CAD-RADS系统诊断冠心病的相关危险因素。结果：与非冠心病组比较，冠心病组患者中男性、高血压、糖尿病和吸烟者所占比例明显升高（P<0.05），冠心病组患者平均年龄大、UA水平高（P<0.05）。多因素Logistic回归分析，年龄和糖尿病是冠状动脉CAD-RADS诊断冠心病的最显著危险因素。结论：CAD-RADS诊断冠心病受到多种危险因素的影响，其中年龄和糖尿病是最显著的独立相关危险因素。

关键词: 冠状动脉粥样硬化性心脏病, 危险因素, CT血管造影, 冠状动脉疾病报告与数据系统

Abstract: Objective: To investigate the application of Coronary Artery Disease-Reporting and Data System (CAD-RADS) in the diagnosis of coronary atherosclerotic heart disease(CAD) and its risk factors, and to clarify the effective strength of different risk factors in the diagnosis of CAD by using CAD-RADS. Methods: All the data of 266 patients, who were initially suspected with CAD and underwent CT angiography, were collected and diagnosed by using CAD-RADS and were divided into CAD group(n=174) and non-CAD group(n=69). The informations of age, gender, hypertension, hyperlipemia, diabetes, smoking, serum uric acid (UA) levels, and plasma fibrinogen (FIB) levels of the patients in two groups were analyzed;single factor analysis and multivariate Logstic regression analysis were used to analyze the risk factors of CAD diagnosed by CAD-RADS. Results: Compared with non-CAD group,the ratios of male, hypertension, diabetes,smoking of the patients in CAD group were increased (P<0.05),and the age and the level of UA of the patients in CAD group were also increased (P<0.05). The Logistic regression analysis results showed that age and diabetes were the independent risk factors for CAD diagnosed by CAD-RADS. Conclusion: There are many independent risk factors for CAD diagnosed by CAD-RADS, and age and diabetes are the most correlated risk factors for CAD.

Key words: Coronary Artery Disease-Reporting and Data System, risk factor, CT angiography, coronary atherosclerotic heart disease

中图分类号:

R445.3

周宏, 刘进才, 罗光华, 谢佩含, 杨娟, 董宇岚, 卿伟鹏, 张晶晶. 冠状动脉疾病报告与数据系统在冠心病患者危险因素分析中的应用[J]. 吉林大学学报(医学版), 2017, 43(03): 617-622.

ZHOU Hong, LIU Jincai, LUO Guanghua, XIE Peihan, YANG Juan, DONG Yulan, QING Weipeng, ZHANG Jingjing. Application of Coronary Artery Disease-Reporting and Data System in risk factor analysis of patients with coronary artery disease[J]. Journal of Jilin University Medicine Edition, 2017, 43(03): 617-622.

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冠状动脉疾病报告与数据系统在冠心病患者危险因素分析中的应用

Application of Coronary Artery Disease-Reporting and Data System in risk factor analysis of patients with coronary artery disease

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