吉林大学学报(医学版) ›› 2018, Vol. 44 ›› Issue (01): 162-165.doi: 10.13481/j.1671-587x.20180131

• 临床医学 • 上一篇    下一篇

五倍子提取液在慢性根尖周炎患者根管治疗中应用的效果评价

车鸿泽1, 车彦海2, 金权1, 许立硕1, 马宁1, 张莉3   

  1. 1. 吉林大学口腔医院牙周病科, 吉林 长春 130021;
    2. 吉林大学口腔医院基础教研室, 吉林 长春 130021;
    3. 吉林大学口腔医院急诊科, 吉林 长春 130021
  • 收稿日期:2017-09-08 出版日期:2018-01-28 发布日期:2018-01-24
  • 通讯作者: 张莉,副教授,硕士研究生导师(Tel:0431-85579359,E-mail:zlamy1009@sina.com);马宁,教授,主任医师,硕士研究生导师(Tel:0431-88796039,E-mail:maningbsh76@sina.com) E-mail:zlamy1009@sina.com;maningbsh76@sina.com
  • 作者简介:车鸿泽(1990-),男,吉林省长春市人,医学硕士,主要从事牙周病学方面的研究。
  • 基金资助:
    吉林省中医药管理局中医药科技项目资助课题(2016061)

Effect evaluation on application of gallnut extract in root canal therapy of patients with chronic periapical periodontitis

CHE Hongze1, CHE Yanhai2, JIN Quan1, XU Lishuo1, MA Ning1, ZHANG Li3   

  1. 1. Department of Periodontics, Stomatology Hospital, Jilin University, Changchun 130021, China;
    2. Department of Basic Teaching and Researching, Stomatology Hospital, Jilin University, Changchun 130021, China;
    3. Department of Emergency, Stomatology Hospital, Jilin University, Changchun 130021, China
  • Received:2017-09-08 Online:2018-01-28 Published:2018-01-24

摘要: 目的:探讨五倍子提取液作为冲洗剂对慢性根尖周炎根管治疗效果的影响,并初步阐明其作用机制。方法:选取在吉林大学口腔医院急诊科就诊的诊断为慢性根尖周炎的患者192例(患牙192颗),随机分为对照组、过氧化氢组、次氯酸钠组和五倍子组(每组48例),在根管治疗过程中分别使用蒸馏水、过氧化氢、次氯酸钠和五倍子提取液作为根管冲洗剂,待根管充填完成后随访观察1周、6个月和12个月的治疗效果并进行对比分析。结果:根充治疗后,临床检查患牙冷热刺激不敏感,叩诊(-),松动度≤Ⅰ°,牙龈无红肿,探诊出血(-),无窦道,正常行使咀嚼功能,X线片显示根尖周骨质透射区减小或消失,则为治疗有效。6个月复诊时,五倍子组患者根管治疗有效率为89.4%,与过氧化氢组和次氯酸钠组有效率(91.1%和91.5%)比较差异无统计学意义(P>0.05),与对照组(67.4%)比较差异有统计学意义(P<0.05);12个月复诊时,五倍子组患者根管治疗有效率为83.7%,与过氧化氢组和次氯酸钠组有效率(83.3%和87.8%)比较差异无统计学意义(P>0.05),与对照组(58.1%)比较差异有统计学意义(P<0.05),且五倍子组患者由好转变为痊愈的比例高于过氧化氢组和次氯酸钠组。结论:五倍子提取液作为根管冲洗剂,具有良好的抑菌和清洁作用,能够达到治愈慢性根尖周炎和防止继发感染的目的。

关键词: 根管治疗, 根管冲洗剂, 五倍子提取液, 慢性根尖周炎

Abstract: Objective: To explore the influence of gallnut extract as a root canal irrigants in the curative effect of chronic periapical periodontitis,and to clarify its mechanism. Methods: A total of 192 patients diagnosed with chronic periapical periodontitis were selected and randomly divided into control group (distilled water),hydrogen peroxide group,sodium hypochlorite group and gallnut extract group (n=48).In the process of root canal treatment,four irrigants were used respectively,then the curative effects 1 week,6 months,12 months after treatment were observed and compared. Results: After root filling treatment,the cold and heat stimulation of the tooth was insensitive in clinical examination,percussion(-),loose degree ≤ Ⅰ°,no swollen gums,bleeding on probing(-),no fistula,normal function of the exercise of chewing,decreased or disappeared transmission area in periapical bone in X-ray photo,and those metioned above were considered effective treatment.After 6 months of treatment,the effective rate in gallnut group was 89.4%,and there were no statistically significant differences compared with hydrogen peroxide group (91.1%) and sodium hypochlorite group(91.5%) (P>0.05),but there was significant difference compared with control group (67.4%) (P<0.05).After root filling treatment for 12 months,the effective rate in gallnut group was 83.7% and there were no statistically significant differences compared with hydrogen peroxide group(83.3%) and sodium hypochlorite group(87.8%) (P>0.05),but the ratio of tooth from improvement to recovery in gallnut group was higher than those in hydrogen peroxide group and sodium hypochlorite group. Conclusion: Gallnut extract as a root canal irrigants has good antibacterial and cleaning effect,and can achieve the aim of curing the chronic root periapical inflammation and preventing the infection.

Key words: chronic periapical periodontitis, root canal irrigants, gallnut extract, root canal therapy

中图分类号: 

  • R781.34