双侧胸腔镜手术治疗侵袭性胸腺瘤并发重症肌无力1例报告及文献复习

doi:10.13481/j.1671-587x.20180135

Abstract

Abstract: Objective: To observe the effect of bilateral thoracoscopic surgery for invasive thymoma complicated with myasthenia gravis, and to explore feasibility of surgical procedure. Methods: Bilateral thoracoscopic extended thymectomy was performed in one patient with invasive thymoma complicated with myasthenia gravis,with complete resection of thymus and anterior mediastinal adipose tissue through bilateral approach,and the curative effect was observed. Results: Bilateral thoracoscopic thymectomy for invasive thymoma had radical effects with rapid recovery after surgery,avoiding large surgical trauma and more complications in open surgery and flawed in removing contralateral fat and ectopic thymus with unilateral thoracoscope. Conclusion: Bilateral thoracoscopic extended thymectomy has radical effects for invasive thymoma complicated with myasthenia gravis,confirming its feasible surgical procedure.

Key words: invasive thymoma, myasthenia gravis, video-assisted thoracoscopic surgery, extended thymectomy

CLC Number:

R746.1

XU Zhenan, SHANG Shengtao, LU Yufeng, ZHANG Ji, CHEN Chong, CHEN Yue, ZHAO Wei. Bilateral thoracoscopic surgery for invasive thymoma complicated with myasthenia gravis: A case report and literature review[J].Journal of Jilin University Medicine Edition, 2018, 44(01): 179-181.

References

[1] Duwe BV,Sterman DH,Musani AI.Tumors of the mediastinum[J].Chest,2005,128(4):2893-2909.
[2] Ichimura H,Usui S,Okazaki H, et al.Excision after chemoradiotherapy of invasive thymoma extending into the right atrium:report of a case[J].Surg Today,2006,36(6):534-537.
[3] Suster S,Moran CA.Thymoma classification:current status and future trends[J].Am J Clin Pathol,2006,125(4):542-554.
[4] LePéchoux C,Mahé M,Bretel JJ,et al.Thymic tumors[J].Cancer Radiother,2005,9(6/7):351-357.
[5] 邹强,赵夏,黄云,等.放化疗联合胸腺瘤切除术治疗重症肌无力合并胸腺瘤的临床效果评价[J].医学综述,2016,22(24):4989-4992.
[6] 张文军.胸腔镜与胸骨正中劈开胸腺扩大切除治疗重症肌无力并胸腺瘤的比较[D].合肥:安徽医科大学,2016.
[7] 吕传真.重症肌无力的临床特征和诊断[J].中国实用内科杂志,1994,6(14):325-326.
[8] Sun XG,Wang YL,Liu YH,et al.Myasthenia gravis appearing after thymectomy[J].J Clin Neurosci, 2011,18(1):57-60.
[9] 钱昆杰,孙清超,张海平,等.胸腺瘤切除术后发生重症肌无力的危险因素分析[J].中国胸心血管外科临床杂志,2017,23(1):20-24.
[10] Pennathur A,Qureshi I,Schuchert MJ,et al.Comparison of surgical techniques for early-stagethymoma:feasibility of minimally invasive thymectomy and comparison with open resection[J].J Thorac Cardiovasc Surg,2011,141(3):694-701.
[11] Gu ZT,Mao T,Chen WH,et al.Comparison of video-assisted thoracoscopic surgery and median sternotomy approaches for thymic tumor resections at a single institution[J].Surg Laparosc Endosc Percutan Tech,2015,25(1):47-51.
[12] Odaka M,Akiba T,Yabe M,et al.Unilateral thoracoscopic subtotal thymectomy for the treatment of stage Ⅰ and Ⅱ thymoma[J].Eur J Cardiothorac Surg,2010,37(4):824-826.
[13] Ng CS,Wan IY,Yim AP.Video-assisted thoracic surgery thymectomy:the better approach[J].Ann Thorac Surg,2010,89(6):S2135-S2141.
[14] Jurado J,Javidfar J,Newmark A,et al.Minimally invasive thymectomy and open thymectomy:outcome analysis of 263 patients[J].Ann Thorac Surg,2012,94(3):974-981.
[15] Ye B,Tantai JC,Ge XX,et al.Surgical techniques for early-stage thymoma:video-assisted thoracoscopic thymectomy versus transsternal thymectomy[J].J Thorac Cardiovasc Surg,2014,147(5):1599-1603.

Bilateral thoracoscopic surgery for invasive thymoma complicated with myasthenia gravis: A case report and literature review

PDF (PC)

Like

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 6

Metrics

Comments

Recommended 0

[1]	HU Yinghua, WANG Tingting, WANG Xichen, WANG Hongfeng. Effect of “Warming Yang and Nourishing Qi” Acupuncture on AChR mRNA expression in neuromuscular junction of rats with experimental autoimmune myasthenis gravis [J]. Journal of Jilin University Medicine Edition, 2016, 42(05): 872-876.
[2]	WANG Xichen, SHEN Aihua, HU Yinghua, WANG Hongfeng. Effect of “Warming Yang and Nourishing Qi” Acupuncture on acetylcholine receptor protein expression in neuromuscular junction of rats with EAMG [J]. Journal of Jilin University Medicine Edition, 2016, 42(02): 200-203.
[3]	PANG Ziqian, WANG Keren, YE Yuqin, ZHANG Xin, LIU Mingjun, HUANG Qingdao. Diagnostic value of exercise test of low-frequency repetitive nerve stimulation in patients with myasthenia gravis [J]. Journal of Jilin University Medicine Edition, 2015, 41(03): 652-655.
[4]	JIA Teng, LI Yang, ZHANG Kewei, GAO Xinliang, ZHANG Kejian, LIU Wei. Clinical application of uniportal video-assisted thoracoscopic pulmonary resection with 100 cases report [J]. Journal of Jilin University Medicine Edition, 2015, 41(01): 165-168.
[5]	WANG Hong-feng,DONG Li，WANG Ting-ting. Influence of “Warming yang and Nourishing qi” acupuncture treatment in serum AchR-Ab and IFN-γ expression levels in rats with experimental autoimmune myasthenia gravis and its mechanism [J]. Journal of Jilin University Medicine Edition, 2014, 40(01): 31-34.
[6]	TONG ti, KE Ji, ZHANG Yan. Comparison of curative effects between video-assisted thoracoscopic extended thymectomy and trans-sternal thymectomy for myasthenia gravis [J]. J4, 2010, 36(4): 767-771.