Abstract:

Objective
To explore the efficacy and influencing factors of interventional therapy for chronic atherosclerotic occlusive disease of the lower extremity. Methods 56 cases of simple atherosclerotic occlusive disease of lower extremity were divided into 3 types according to the location of occlusion,including 17 cases of abdominal aorta-iliac artery,18 cases of iliac-femoral artery,and 21 cases of femoropopliteal inferior genicular artery. Catheter and guide were combined with blunt dissection and subtle banding were used to dredge the occluded vessels,and the stents were implanted when interlayer appeared. Results  After the treatment,46 cases of occlusion were dredged (82.1%),6 cases remained occluded with the same symptoms (10.7%),and 4 cases had severer symptoms (7.1%). Among the 46 successful cases,there were 16 cases of abdominal aorta-iliac artery (94.1%),16 cases of iliac-femoral artery (88.9%) and 14 cases of femoropopliteal inferior genicular artery(66.6%). There was no statistical difference between the abdominal aorta-iliac artery cases and iliac-femoral artery cases (P>0.05),but the rate of abdominal aorta-iliac artery was higher than that of femoropopliteal inferior aorta-iliac artery (P<0.05).In the successful cases,9 cases of abdominal aorta-iliac artery (52.9%),10 cases of iliac-femoral artery (55.5%) and 7 cases of femoropopliteal inferior genicular artery (33.3%) had 5-10 cm of occlusion,there was no significant difference between the first two types(P>0.05),but there were significant differences between the first two types and the third type (P<0.05).Compared with the 14 dredged cases (71.4%),7 cases (33.3%) of undredged femoropopliteal inferior genicular artery cases had richer compensatory circulation (P<0.05). Conclusion It is safe and effective to treat simple atherosclerotic occlusive disease of the lower extremity with interventional therapy. The location and length of occlusion and the abundance of compensatory circulation have effects on the therapy.

Key words: atherosclerosis;arterial occlusive diseases;interventional therapy;effect evaluation