低频重复神经电刺激疲劳试验对重症肌无力患者的诊断作用

doi:10.13481/j.1671-587x.20150341

Abstract

Abstract:

Objective To perform the exercise test of low-frequency repetitive nerve stimulation(RNS) in the patients with myasthenia gravis(MG), and to clarify the diagnostic value of exercise test in the patients with MG. Methods 30 patients with MG were collected.The RNS at rest and exercise test in facial nerve were performed in all patients.Exercise test was performed at fatigue 1 min and 2 min, then the RNS was performed at the ending of fatigue, 1 min and 2 min after fatigue, respectively.The decreasing degree of compound muslce action potential (CMAP) amplitude at different time points were analyzed. Results The CMAP amplitudes in exercise test of RNS were decreased significantly when compared with RNS at rest at different time points, especially at fatigue 2 min and rest 1 min.Amang 30 patients, 12 patients had normal RNS at rest, but all of them had abnormal RNS after exercise test. Conclusion Exercise test of RNS has the diagnostic value in the patients with MG, especially in the patients with normal RNS at rest.Fatigue 2 min and rest 1 min could be considered when performing exercise test of RNS.

Key words: myasthenia gravis, repetitive nerve stimulation, exercise test

CLC Number:

R746.1

PANG Ziqian, WANG Keren, YE Yuqin, ZHANG Xin, LIU Mingjun, HUANG Qingdao. Diagnostic value of exercise test of low-frequency repetitive nerve stimulation in patients with myasthenia gravis[J].Journal of Jilin University Medicine Edition, 2015, 41(03): 652-655.

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Diagnostic value of exercise test of low-frequency repetitive nerve stimulation in patients with myasthenia gravis

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