Abstract: Objective: To study the pathogenesis and the risk factors of eye injury after non-ocular surgery in the patients underwent general anesthesia, and to provide the reference for its prevention,diagnosis and treatment.Methods: The clinical materials of two patients with eye injury after non-ocular surgery underwent general anesthesia were analyzed and the related literatures were reviewed.Results: A young woman patient underwent laparoscopic hysterectomy with general anesthesia while positioned Trendelenburg,the eyes were being closed naturally without protection,and corneal abrasion of both eyes occurred after operation. The lesion had completely resolved with no sequelae after treatment.An old man underwent cervical posterior laminoplasty with general anesthesia in prone position developed ischemic optic neuropathy(ION) after operation. The vision of the patients partly recovered after symptomatic treatment.Conclusion: Corneal abrasion is the most frequent ophthalmologic complication during general anesthesia,most of the patients have good prognosis. Postoperative visual loss(POVL) is the most severe ophthalmologic complication without effective treatment available,the delicate reasons and mechanisms are not totally clear,prevention outweighs treatment.

Key words: general anesthesia, eye injury, corneal abrasion, postoperative visual loss, ischemic optic neuropathy, central retinal artery occlusion