Journal of Jilin University(Medicine Edition) ›› 2021, Vol. 47 ›› Issue (6): 1557-1561.doi: 10.13481/j.1671-587X.20210629

• Clinical medicine • Previous Articles     Next Articles

Spindle cell carcinoma of lung: A case report and literature review

Qian LI,Jiaqi ZHOU,Jingyi YUAN,Min ZHAO,Xin DI,Ke WANG()   

  1. Department of Respiratory and Critical Care Medicine,Second Hospital,Jilin University,Changchun 130041,China
  • Received:2021-04-27 Online:2021-11-28 Published:2021-12-14
  • Contact: Ke WANG E-mail:kewangm1@hotmail.com

Abstract: Objective

To investigate the clinical features, diagnosis and treatment of the patients with spindle cell carcinoma of lung (SpCC), in order to improve the clinicians’understanding of this disease.

Methods

The clinical data, imaging manifestations, bronchoscope findings,and pathological findings of 1 patient with SpCC were collected, the above data were analyzed, and the relevant literatures were reviewed.

Results

A 71-year-old male patient was hospitalized due to cough and shortness of breath for 1 month.The physical examination results showed that the left thoracic cavity was depressed, the intercostal space was narrow, and the trachea shifted to the left;the dullness of left lung was detected by percussion, and the breath sounds of left lung disappeared without other obvious positive signs. The chest CT results showed the high-density shadow in the left airway and the reduced volume of left lung.The fiberoptic bronchoscope results showed that there were pedicled neoorganisms blocking the airway in the left main bronchus. The pathological examination results showed that the adenopapilloma of the bronchus was formed with scalification. After admission,the chest enhanced CT examination results showed the strip-shaped soft tissue density shadow of the left main bronchus,which showed mild enhancement in enhanced scan;the volume of left lung was reduced with strip-like soft tissue density shadow, which showed uneven enhancement in enhanced scan. After comprehensive laboratory and imaging examination, the possibility of bronchial benign tumor was considered, and two times of bronchoscopic electrical traps were performed. The final bronchoscopic lung biopsy showed a large number of spindle cells.Combined with the immunohistochemical staining results, SpCC was diagnosed.

Conclusion

SpCC is a special type of epithelial-derived tumor and it is easily misdiagnosed due to its similar morphology to sarcoma.The SpCC patients with main bronchial space occupying lesions accompanying with atelectasis as the main imaging manifestations are relatively rare, and SpCC should be differentiated from the bronchial benign tumor.

Key words: sarcomatoid carcinoma, spindle cell carcinoma, imaging manifestation, fiber bronchoscope, case report

CLC Number: 

  • R563.9