Abstract:

Objective
To study the clinical effect of Qiliqiangxin capsule (QC)  in patients with  chronic congestive heart failure (CHF). Methods According to random number table,64 CHF patients were randomly assigned into therapy group (n=33) and control group (n=31).During the treatment,sweat secretion,heart function improved rate,6 min walking distance,the side-effect and compliance were observed.The levels of serum Na+ and K+ of patients were measured on the 2nd,8th and 15th hospital day.Results  Compared with control group,the remission rate  of sweat secretion in therapy group was higher after treatment (P<0.05).One week later,heart function and 6 min walking distance were improved in both groups,but there was no significant difference between two groups（P>0.05）;compared with control group,the improved rates of heart function and 6 min walking distance in therapy group were higher after two weeks (P<0.05).There was no significant difference between two groups of the level of serum Na+ on the 8th hospital day（P>0.05）；on the 15th day,the level of serum Na+ in therapy group was higher than that in control group (P<0.05). There were no significant differences between two groups of the level of serum K+ on the 8th or 15th hospital day（P>0.05）.During treatment,33 patients had not any uncomfortable complain about this drug and nobody stopped using this capsule;while there was no complain from the patients of control group.Conclusion  The effect of QC about releasing hyperidrosis in a short time is conspicuous.QC can improve heart function,but it plays this role gradually.QC can keep the level of serum Na+ to some extent.There is no influence on the level of serum K+.The tolerance of this capsule is well.

Key words: heart failure,congestive, Qiliqiangxin capsule;electrolyte disturbances;hyponatremia