关键词: 生物药物学, 抗菌肽, 凝胶剂, 抑菌试验

Abstract: To prepare antimicrobial peptide gel and to research its invitro antimicrobial activity, To prepare antimicrobial peptide gel and to research its invitro antimicrobial activity, ultraviolet spectrophotometry was used to determine the content of the antimicrobial peptide, and orthogonal test was employed to determine the prescription, and cylinder plate method was used to detect the effects of antimicrobial peptide gel on the following bacteria: Pseudomonas aeruginosa, Staphylocococus aureus, Escherichia coli and different species of resistant Grampositive or resistant Gramnegative bacteria. Experimental results show that antimicrobial peptide gel has significant effect invitro growth inhibition on bacteria.The preparation method is feasible and the gel is stable.

Key words: biological pharmaceuticals, antimicrobial peptide, gel, resistant bacterium