盐酸异丙嗪和盐酸氯丙嗪的示波极谱滴定分析

盐酸异丙嗪和盐酸氯丙嗪的示波极谱滴定分析

于铁力¹, 孟昭仁2

1. 北华大学公共基础部，吉林 132001;2.北华大学师范理学院化学系，吉林 132013

收稿日期:2002-04-29 修回日期:1900-01-01 出版日期:2003-01-26 发布日期:2003-01-26
通讯作者: 孟昭仁

Determination of Promethazine Hydrochloride and Chloropromazine Hydrochloride by Oscillopolarographic Titration

YU Tie-li, MENG Zhao-ren²

1. Department of Public Base, Beihua University, Jilin 132001, China; 2. Department of Chemistry, Teachers College of Science, Beihua University, Jilin 132013, China

Received:2002-04-29 Revised:1900-01-01 Online:2003-01-26 Published:2003-01-26
Contact: MENG Zhao-ren

摘要/Abstract

摘要： 在0.5 mol/L NaAc-HAc(pH=5.4)介质和底液条件下，盐酸异丙嗪和盐酸氯丙嗪可与Na-TPB反应生成沉淀，以在示波极谱图上切口出现TPB沉淀指示滴定终点. 此法用于盐酸异丙嗪和盐酸氯丙嗪药物制剂的直接滴定，获得了满意结果.

关键词: 示波极谱, 四苯硼钠, 滴定, 盐酸异丙嗪, 盐酸氯丙嗪

Abstract: Promethazine hydrochloride and chloropromazine hydrochloride were determined by oscillopolarographic titration with sodium tetraphenylborate(Na-TPB) as titrant. TPB gives a sharp oscillopolarographic incision in 0~5 mol/L NaAc-HAc(pH=5.4), which can be used to indicate the end point of the titration. The characteristics of the method are simple, quick and exact. The results are satisfactory.

Key words: oscillopolarography, sodium tetraphenylborate, titration, promethazine hydrochloride, chloropomazine hydrochloride

中图分类号:

O657.14

于铁力, 孟昭仁. 盐酸异丙嗪和盐酸氯丙嗪的示波极谱滴定分析[J]. J4, 2003, 41(01): 115-116.

YU Tie-li, MENG Zhao-ren. Determination of Promethazine Hydrochloride and Chloropromazine Hydrochloride by Oscillopolarographic Titration[J]. J4, 2003, 41(01): 115-116.