J4 ›› 2012, Vol. 50 ›› Issue (01): 153-.

• 生命科学 • 上一篇    

次血红素六肽对纳米金诱导线虫热激损伤的保护作用

郭常闰1, 关树文1, 黄磊1, 张超1, 董彪2, 宋宏伟2, 王丽萍1   

  1. 1. 吉林大学 生命科学学院, 长春 130012; 2. 吉林大学 电子科学与工程学院, 长春 130012
  • 收稿日期:2011-05-27 出版日期:2012-01-26 发布日期:2012-03-06
  • 通讯作者: 王丽萍 E-mail:wanglp@jlu.edu.cn

DhHP6 Protection of Caenorhabditis elegans from Heat Shock Injury Induced by Au Nanoparticles

GUO Changrun1, GUAN Shuwen1, HUANG Lei1, ZHANG Chao1,DONG Biao2, SONG Hongwei2, WANG Liping1   

  1. 1. College of Life Science, Jilin University, Changchun 130012, China;2. College of Electronic Science and Engineering, Jilin University, Chang
    chun 130012, China
  • Received:2011-05-27 Online:2012-01-26 Published:2012-03-06
  • Contact: WANG Liping E-mail:wanglp@jlu.edu.cn

摘要:

通过考察Au纳米球壳对野生型秀丽隐杆线虫的光热转换作用, 建立一种新型的秀丽线虫热激损伤模型. 实验结果表明, 在纳米金浓度为30 μmol/L, 红外光强为3 W/cm2, 照射8 min的热激条件下加入次血红素六肽对线虫有保护作用.

关键词: Au纳米球壳; 秀丽隐杆线虫; 热激; 次血红素六肽

Abstract:

Using the lightheat conversion induced by Au nanoparticles, we created a new experimental method of heatshock for Caenorhabditis
elegans. DhHP6 is a mimetic peroxidase designed and synthesised by our laboratory. C.elegans was incubated with Au nanoparticles at the concentration of 30 μmol/L and exposed to the infrared lights at a intensity of 3 W/cm2 for 8 min. The results showed that DhHp\|6 had protective effect on the C.elegans in this heat\|shock conditions.

Key words: Au nanoparticles, Caenorhabditis elegans, heat shock, DhHP-6

中图分类号: 

  • Q613