Abstract: We studied the effect of Fenton advanced oxidation on the removal of levofloxacin hydrochloride in water, and investigated the effects of n(H₂O₂)∶n(Fe²⁺), H₂O₂ dosage, initial pH value, reaction time and initial mass concentration on the removal efficiency. The results show that the removal rates of levofloxacin hydrochloride, chemical oxygen demand (by K₂Cr₂O₇, COD_Cr) and total organic carbon (TOC) increase first and then decrease with the increase of n(H₂O₂)∶n(Fe²⁺) in the range of 5—25. When the dosage of H₂O₂ was 15 mL/L, the removal rates of levofloxacin hydrochloride, COD_Cr and TOC are 88.40%, 59.52% and 33.80%, respectively. When pH=3, the removal rates of levofloxacin hydrochloride, COD_Cr and TOC are 9240%,5952% and 3451%, respectively. The removal rate of levofloxacin hydrochloride, COD_Cr and TOC gradually increase with the time, and the removal rate decrease with the initial mass concentration. When the reaction time is 3 h, the removal process is basically comp
leted. The effect of Fenton advanced oxidation on the removal of levofloxacin hydrochloride in water is the best at the conditions of pH=3, temperature is 20 ℃, H₂O₂ dosage is 15 mL/L, n(H₂O₂)∶n(Fe²⁺)=10, the removal efficiency is 96.40%.

Key words: total organic carbon (TOC), levofloxacin hydrochloride, Fenton reation, chemical oxygen demand (COD)