吉林大学学报(医学版)

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全胸腔镜肺叶切除与开胸肺叶切除治疗老年肺癌的疗效比较

林星宇,杨志广,张 鹏,邵国光   

  1. 吉林大学第一医院胸外科,吉林 长春 130021
  • 收稿日期:2014-03-20 出版日期:2014-11-28 发布日期:2015-01-18
  • 通讯作者: 邵国光 (Tel:0431-88782299,E-mail:guoguangshao@sohu.com) E-mail:guoguangshao@sohu.com
  • 作者简介:林星宇(1986-),男,吉林省吉林市人,在读医学博士,主要从事肺癌的 诊断及治疗研究。
  • 基金资助:

     卫生与计划生育委员会部属医院临床学科重点项目资助课题(W2011FAI16)

Comparison of curative effects of lobectomy between C-VATS 
and thoracotomy in aged patients with  lung cancer


LIN Xing-yu,YANG Zhi-guang,ZHANG Peng,SHAO Guo-guang   

  1. Department of Thoracic Surgery,Frist Hospital,Jilin University,Changchun 130021,China
  • Received:2014-03-20 Online:2014-11-28 Published:2015-01-18

摘要:

目的:探讨全胸腔镜肺叶切除(C-VATS)与传统开胸肺叶切除治疗老年肺癌疗效的差异,阐
明全胸腔镜的独特临床疗效。方法:选择65岁以上无糖尿病、慢性支气管炎、心脏疾患等并发
症的肺癌手术患者80例,按患者意愿选择手术方式,全胸腔镜组(C-VATS)40例,开放手
术组(OPEN)40例,比较2组患者手术时间、淋巴结清扫数量、术中失血量、术后胸引量、带
管时间、术后住院时间、疼痛程度、术后并发症发生率、术前及术后平均静息心率等。结果:C-V
ATS组手术时间[(193.12±59.06) min]长于OPEN组[(167.17±54.01) min](P<0.05);C-VATS
组淋巴结清扫数量[(14.6±7.5)枚]与OPEN组[(15.2±4.5)枚]比较差异无统计学意
义(P>0.05);术后疼痛程度(线性视觉模拟评分)C-VATS组(2.54±0.12)较OPEN组(4.61±
0.10)明显减轻(P<0.05);C-VATS组术后平均带管时间[(6.41±3.32) d]少于OPEN组[(11.67±4.13)
 d](P<0.05);C-VATS组术后住院时间[(8.52±3.25) d]少于OPEN组[(14.76±6.11) d]
(P<0.05);C-VATS组术中失血量[(231.28±203.15) mL]与OPEN组[(213.33±187.18) mL]比较差异无
统计学意义(P>0.05);C-VATS组术后胸引量[(1 597.83±1 049.29) mL]与OPEN组[(1 690.68±1 043.37) mL]比较差异无统计学意义(P>0.05);C-VATS组术后常见并发症发生率与OPEN组比较差异无统计学意义(P>0.05)。C-VATS 组和OPEN组患者术后静息心率均显著高于术前;患
者术后静息心率C-VATS组于术后第3天恢复至术前水平,OPEN组于术后第7天恢复至术前水平。结论:C-VATS相对传统开胸手术,创伤小、疼痛轻、术后恢复快,临床上适合老年患者应用。

关键词: 肺肿瘤, 全胸腔镜肺叶切除, 开胸肺叶切除术, 淋巴结清扫

Abstract:

Objective To investigate the difference  of curative effects between the complete video assisted thoracic surgery (C-VATS) and traditional open surgery
 in the treatment of elderly patients with lung cancer, and to clarify the specially curative effect of C-VATS.Methods 80 patients with lung cancer without diabetes mellitus,chronic brouchitis and heart diseases aged over 65 years were enrolled in the study.They were divided into  C-VATS group and open surgery for lobectomy (OPEN) group (n=40) according their wishes. The operation time,number of lymph nodes removed,amount of intraoperative blood loss,postoperative thoracic drainage,chest tube duration,postoperative hospitalized time,postoperative pain degree,incidence of postoperative complications,preoperative and postoperative sedentary heart rate (HR) of the patients in two groups were compared.Results The operation time in C-VATS group(193.12 min±59.06 min) was longer than that in OPEN group(167.17 min±54.01 min)(P<0.05),and the number of lymph nodes removed in C-VATS group(14.6±7.5) had no significant difference compared with OPEN group(15.2±4.5)(P>0.05).The postoperative pain degree in C-VATS
 group(2.54±0.12) was lower than that in OPEN group(4.61±0.10)(P<0.05);the postoperative chest rube duration in C-VAS group(6.14 d±3.32 d) was shorter than that in   OPEN group  (11.67 d±4.13 d);the postperative hospitalized time in C-AVA group(8.52 d±3.25 d)was shorter than that in OPEN group

(14.76 d±6.11 d)(P<0.05).There were no significant differences of intraoperative blood loss(231.28 mL±203.15 mL vs 213.33 mL±187.18 mL),postoperative thoracic draginage(1 597.83 mL±1 049.29 mL vs  1 690.68 mL±1 043.37 mL),incidence of postoperative complications between C-VATS group and OPEN group(P>0.05).The postoperative sedentary HR in C-VATS group and  OPEN group were significantly higher than preoperative;the  postoperative sedentary HR recovered  to the preoperative level 3 d after operation in C-VATS group and it  recovered to the preoperative level  7 d after operation  in OPEN group.Conclusion Compared with traditional open thoracic surgery, C-VATS    owns the characteristics such as less trauma,less pain
,less hospital stay and better postoperative recovery in the aged patients with lung cancer.

Key words: lung neoplasms, video-assisted thoracoscopic lobectomy, thoracotomy lobectomy, lymph node dissection

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