孕11~40周正常胎儿静脉导管血流频谱变化规律及其临床意义

doi:10.13481/j.1671-587x.20180137

吉林大学学报(医学版) ›› 2018, Vol. 44 ›› Issue (01): 186-189.doi: 10.13481/j.1671-587x.20180137

孕11~40周正常胎儿静脉导管血流频谱变化规律及其临床意义

李丽芳¹, 叶真²

1. 福建省厦门市妇幼保健院超声科, 福建厦门 361003;
2. 福建医科大学第一临床医学院超声科, 福建福州 350005

收稿日期:2017-05-08 出版日期:2018-01-28 发布日期:2018-01-24
通讯作者: 叶真,教授,硕士研究生导师(Tel:0591-87982337,E-mail:chenyezhen@gmail.com) E-mail:chenyezhen@gmail.com
作者简介:李丽芳(1970-),女,福建省漳州市人,主任医师,医学硕士,主要从事妇产科超声方面的研究。
基金资助:
福建省卫计委医学创新项目资助课题（2009-CXB-65）

Change rule of ductus venosus blood flow spectrum of normal fetal of 11-40 weeks and its clinical significance

LI Lifang¹, YE Zhen²

1. Department of Ultrasound, Maternal and Child Health Care Hospital, Xiamen City, Fujian Province, Xiamen 361003, China;
2. Department of Ultrasound, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

Received:2017-05-08 Online:2018-01-28 Published:2018-01-24

摘要/Abstract

摘要： 目的：探讨正常胎儿静脉导管（DV）血流频谱的正确检测方法及正常胎儿DV的血流频谱随孕周变化的规律，建立DV血流各参数的参考值范围。方法：以320例孕11~40周正常单胎孕妇为研究对象，应用彩色多普勒超声诊断仪，在超声标准切面上测得胎儿DV血流频谱中的心室收缩期峰值速度（SV）、心房收缩期波谷峰值速度（aV）、搏动指数（PI）和阻力指数（RI），计算SV与aV的比值（S/a），并进行统计学分析。结果：正常胎儿DV血流的多普勒频谱表现为同向三相波，SV随胎龄增长而逐渐升高（F=27.00，P=0.000），aV随胎龄增长明显升高（F=389.81，P<0.01），而PI（F=65.41，P<0.01）、RI（F=58.82，P<0.01）和S/a（F=47.79，P<0.01）则随胎龄的增加而减低。结论：正常胎儿DV的彩色多普勒超声表现为血流峰值速度随胎龄增长而升高，而PI、RI和S/a则随胎龄的增加而减低，其中RI的降幅最大，具有重要的诊断价值。

关键词: 胎儿, 静脉导管, 血流频谱, 彩色多普勒超声

Abstract: Objective: To explore the correct test ways of the ductus venosus(DV) blood flow spectrum of the normal fetal and the rule of changes of the normal fetal DV blood flow spectrum along with gestational week,and to establish the reference ranges of the parameters of blood flow. Methods: A total of 320 cases of single fetal pregnant women within 11-40 weeks were selected as the objects.Using color doppler echocardiography,the ventricular systolic peak velocity(SV),atrial systolic trough(aV),pulse index(PI) and resistance index(RI) were measured,and the ratio of ventricular systolic peak velocity trough ratio(S/a) from ultrasonic standard section was calculated.All of these were analysed statistically. Results: The doppler spectrum of normal fetal DV blood flow showed the same three-phase waves,SV was increased with the increase of gestational age(F=27.00,P=0.000),and aV was elevated with the increase of gestational age(F=389.81,P=0.000),while PI(F=65.41,P=0.000),RI(F=58.82,P=0.000) and S/a ratio(F=47.79,P=0.000) were decreased with the increase of gestational age. Conclusion: The performance of color Doppler flow imaging of normal fetal DV showed that the blood flow peak speed is increased along with the increase of gestational age and PI,RI and S/a are reduced with the increase of gestational age,and RI has the largest decline,which has important diagnosis value.

Key words: change rule, ductus venosus, flow spectrum, fetal

中图分类号:

R741.1

李丽芳, 叶真. 孕11~40周正常胎儿静脉导管血流频谱变化规律及其临床意义[J]. 吉林大学学报(医学版), 2018, 44(01): 186-189.

LI Lifang, YE Zhen. Change rule of ductus venosus blood flow spectrum of normal fetal of 11-40 weeks and its clinical significance[J]. Journal of Jilin University Medicine Edition, 2018, 44(01): 186-189.

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孕11~40周正常胎儿静脉导管血流频谱变化规律及其临床意义

Change rule of ductus venosus blood flow spectrum of normal fetal of 11-40 weeks and its clinical significance

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